UniProt Accession

 NOP15_YEAST; P53927; D6W171 

Genbank Protein ID

 Z69382; Z71386; AY693098; BK006947 

Genbank Nucleotide ID

 CAA93397.1; CAA95989.1; AAT93117.1; DAA10437.1 

Protein Name

 Ribosome biogenesis protein 15 

Protein Synonyms/Alias

 Nucleolar protein 15 

Gene Name

 NOP15 

Gene Synonyms/Alias

 YNL110C; N1954 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
16	STKETVTKQPTEEKP	acetylation	[1]
187	KKRVLVEKGITKPVK	acetylation	[1]

Reference

 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 

Functional Description

 Involved in the biogenesis of the 60S ribosomal subunit. Required for pre-rRNA processing and cytokinesis. Associates with the precursors of the 25S and 5.8S rRNAs. 

Sequence Annotation

 DOMAIN 91 169 RRM.  

Keyword

 Complete proteome; Cytoplasm; Nucleus; Reference proteome; Ribonucleoprotein; Ribosome biogenesis; RNA-binding; rRNA processing. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 220 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005730; C:nucleolus; IDA:SGD.
 GO:0030687; C:preribosome, large subunit precursor; IDA:SGD.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
 GO:0000915; P:cytokinesis, actomyosin contractile ring assembly; IMP:SGD.
 GO:0042273; P:ribosomal large subunit biogenesis; IPI:SGD.
 GO:0006364; P:rRNA processing; IEA:UniProtKB-KW. 

Interpro

 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom. 

Pfam

 PF00076; RRM_1 

SMART

 SM00360; RRM 

PROSITE

 PS50102; RRM 

PRINTS