UniProt Accession

 D4ABT0_RAT; D4ABT0 

Genbank Protein ID

 AABR06097150; AABR06097151; AABR06097152; AABR06097153; AABR06097154 

Genbank Nucleotide ID

  

Protein Name

 Guanine nucleotide-binding protein G(o) subunit alpha 

Protein Synonyms/Alias

  

Gene Name

 Gnao1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
24	KAIEKNLKEDGISAA	acetylation	[1]
24	KAIEKNLKEDGISAA	ubiquitination	[2]
32	EDGISAAKDVKLLLL	acetylation	[1]
32	EDGISAAKDVKLLLL	ubiquitination	[2]
35	ISAAKDVKLLLLGAG	acetylation	[1]
35	ISAAKDVKLLLLGAG	ubiquitination	[2]
54	STIVKQMKIIHEDGF	acetylation	[1]
54	STIVKQMKIIHEDGF	ubiquitination	[2]
98	LGVEYGDKERKADSK	acetylation	[1]
98	LGVEYGDKERKADSK	ubiquitination	[2]
101	EYGDKERKADSKMVC	acetylation	[1]
105	KERKADSKMVCDVVS	acetylation	[1]
154	YQLNDSAKYYLDSLD	acetylation	[1]
154	YQLNDSAKYYLDSLD	ubiquitination	[2]
181	DILRTRVKTTGIVET	ubiquitination	[2]
272	IILFLNKKDIFEEKI	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; GTP-binding; Nucleotide-binding; Reference proteome; Transducer. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 354 AA 

Protein Sequence

Gene Ontology

 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0003924; F:GTPase activity; IEA:InterPro.
 GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
 GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; IEA:InterPro. 

Interpro

 IPR001408; Gprotein_alpha_I.
 IPR001019; Gprotein_alpha_su.
 IPR011025; GproteinA_insert.
 IPR027417; P-loop_NTPase. 

Pfam

 PF00503; G-alpha 

SMART

 SM00275; G_alpha 

PROSITE

  

PRINTS

 PR00318; GPROTEINA.
 PR00441; GPROTEINAI.