CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028779
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Glycerol-3-phosphate dehydrogenase, mitochondrial 
Protein Synonyms/Alias
  
Gene Name
 Gpd2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
510DKAFEVAKMASVTGKubiquitination[1]
652RYKKRFHKFDEDEKGacetylation[2]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 745 AA 
Protein Sequence
MAFQKAVKGT ILVGGGALAT VLGLSPFAHY RRKQVSLAYV EAAGYLTEPV NREPPSREAQ 60
LMTLKNTPEF DILVIGGGAT GCGCALDAVT RGLKTALVER DDFSSGTSSR STKLIHGGVR 120
YLQKAIMNLD VEQYRMVKEA LHERANLLEI APHLSAPLPI MLPLYKWWQL PYYWVGIKMY 180
DLVAGSQCLK SSYVLSKSRA LEHFPMLQKD KLVGAIVYYD GQHNDARMNL AIALTAARYG 240
AATANYMEVV SLLKKTDPET GKERVSGARC KDVLTGQEFD VRAKCVINAS GPFTDSVRKM 300
DDKNVVPICQ PSAGVHIVMP GYYSPENMGL LDPATSDGRV IFFLPWEKMT IAGTTDTPTD 360
VTHHPIPSEE DINFILNEVR NYLSSDVEVR RGDVLAAWSG IRPLVTDPKS ADTQSISRNH 420
VVDISDSGLI TIAGGKWTTY RSMAEDTVDA AVKFHNLNAG PSRTVGLFLQ GGKDWSPTLY 480
IRLVQDYGLE SEVAQHLAKT YGDKAFEVAK MASVTGKRWP VVGVRLVSEF PYIEAEVKYG 540
IKEYACTAVD MISRRTRLAF LNVQAAEEAL PRIVELMGRE LNWSELRKQC VTYDSDGSTV 600
ATSWSSQEEL ETATRFLYYE MGYKSRTEQL TDSTEISLLP SDIDRYKKRF HKFDEDEKGF 660
ITIVDVQRVL ESINVQMDEN TLHEILCEVD LNKNGQVELH EFLQLMSAVQ KGRVSGSRLA 720
ILMKTAEENL DRRVPIPVDR SCGGL 745 
Gene Ontology
 GO:0009331; C:glycerol-3-phosphate dehydrogenase complex; TAS:MGI.
 GO:0005743; C:mitochondrial inner membrane; IDA:MGI.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0004368; F:glycerol-3-phosphate dehydrogenase activity; IEA:InterPro.
 GO:0006094; P:gluconeogenesis; IMP:MGI.
 GO:0006072; P:glycerol-3-phosphate metabolic process; IMP:MGI. 
Interpro
 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom.
 IPR006076; FAD-dep_OxRdtase.
 IPR000447; G3P_DH_FAD-dep. 
Pfam
 PF01266; DAO
 PF13499; EF_hand_5 
SMART
 SM00054; EFh 
PROSITE
 PS00018; EF_HAND_1
 PS50222; EF_HAND_2
 PS00977; FAD_G3PDH_1
 PS00978; FAD_G3PDH_2 
PRINTS
 PR01001; FADG3PDH.