UniProt Accession

 A6ZJ79_HUMAN; A6ZJ79 

Genbank Protein ID

 Z83838; Z93244; Z98743 

Genbank Nucleotide ID

  

Protein Name

 Rho GTPase-activating protein 8 

Protein Synonyms/Alias

  

Gene Name

 ARHGAP8 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
95	GWLQSAYKEFDRKYK	ubiquitination	[1]
166	EVLRYDEKLQSLHEG	ubiquitination	[2]
201	GVSLQYLKDKNQGEL	ubiquitination	[2]
251	QRLYNQGKPVNFDDY	ubiquitination	[2]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 305 AA 

Protein Sequence

Gene Ontology

 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0007165; P:signal transduction; IEA:InterPro. 

Interpro

 IPR001251; CRAL-TRIO_dom.
 IPR008936; Rho_GTPase_activation_prot.
 IPR000198; RhoGAP_dom. 

Pfam

 PF00620; RhoGAP 

SMART

 SM00324; RhoGAP
 SM00516; SEC14 

PROSITE

 PS50191; CRAL_TRIO
 PS50238; RHOGAP 

PRINTS