CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028764
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Neb 
Protein Synonyms/Alias
  
Gene Name
 Neb 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
326NDVIQARKAYDLQSDubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 3044 AA 
Protein Sequence
MTSSVEPICI KIKILKSLKE KYKYIICLFL CCFFFFNHNF STNTKKVTES SWATTWVSAA 60
CKMTPSWYGL YMLLRSRVTE NTRKPMRSRK NVYKSDLEWM KGIGWLTEGS VEVMRVKNAQ 120
NLLNERLYRI RPEAYKFTSI VDTPEVILAK TNALQISEPL YRDAWDKEKA NVNVPADIPV 180
MLQSKLNAIQ ISNKHYQKAW EDVKMTGYDI RADAIGIQHA KASRDIASDY LYKTAYEKQK 240
GHYIGCPSAK EDPKLVWAAN VLKMQNDRLY KKAYNDHKAK ISIPVDMVSI NAAKEGQALA 300
SNVDYRQYLH QWSCFPDQND VIQARKAYDL QSDAIYKADL EWLRGIGWMP EGSPEVLRVK 360
NAQEILCDSV YRTPVVKLKY TSIVDTPEVV LAKSNAENIS IPKYREVWDK DKTSIHIMPD 420
TPEINLARAN ALNVSNKLYR EGWDEVKMSC DVRLDAIPIQ AAKASREIAS DYKYKLDHEK 480
QKGHYVGTLT ARDDNKIRWA LIAGKIQNER EYRLQWAKWK TKFQSPVDML SILHSKKCQT 540
LVSDIDYRNY LHEWTCMPDQ NDVIQAKKAY ELQSDAVYKA DLEWLRGIGW MPNDSVSVNH 600
AKHAADIFSE KKYRTKIETL NFTPVDDRVD YVTAKQSSEI RDDIKYRKDW NAIKSKYTLT 660
ETPLLHTAQE AARILDQYLY KEGWEKQKAT GYILPPDAVP FVHAHHSSDV QSELKYKAEH 720
VKQRGHYVGV PTMRDDPKLV WFEHAGQIQN DRLYKESYHK SKAKINIPAD MVSVVAAKEG 780
QNLVSDIDYR QYLHQWTCHP DQNDVIQAKI AYDLQSDNVY KADLEWLRGI GWIPLDSVDH 840
VRVTKNQEMV NQIKYKKDAL ANYPNFTSVE DPPEIVLAKI NSVNQSDVKY KETFNKAKGK 900
YIFSPDTPYI SHSKDMGKLY STILYKGAWE GTKAYGYTLD ERYIPIVGAK HADLVNSELK 960
YKETYEKQKG HYLAGKEISE FPGVVHCLDF QQMRSALNYR RDYEDTKANV HIPNDMMNHV 1020
LAKRCQYILS DLEYRHYFHQ WTSLPEEPNV IRARNAQEIL SDNVYKDDLN WLKGIGCYVW 1080
DTPQILHAKK SYDLQSQLQY TAASKENLQN YNLVTDTPVY VTALQSGINA SEVKYKENYH 1140
QIKDKYTTVL ETADYDRTKH LKSLYSSNIY KEAWDKVKAT SYNLPTSTLS LTHAKNQKHL 1200
ASHIKYREEY EKFKALYTLP KSVDDDPNTA RCLRVGKLNI DRLYRSVYEK NKMKINIVPD 1260
MVEMVTAKDS QKKVSEIDYR LHLHEWICHP DLQVNSHVRK VTDQISDIVY KDDLTWLKGI 1320
GCYVWDTPEI LHAKHAYDLR NDIKYKAHVQ KTRNDYKLVT DTPVYVQAVK SGKQLSDAVY 1380
HYDYVHSVRG KVAPTTKTVD LDRALHAYKL QSENLYKKGL RFLPTGYRLP VDTPHFNHTK 1440
DTRYMSSYFK YKEAYEHIKA NGYTLGPKDV PFVHVRRVNN VTSERLYREL YHKLKDKIHT 1500
TPDTPEIRQV KKTQEAVSEL IYKSDFFKMQ GHMISLPYTP QVLHCRYVGD ITSDIKYKED 1560
LQILKGLGCF LYDTPDMVRS RHLRKLWSNY LYTDNARKMR DKYKVVLDTP EYRKVQELKT 1620
HLSELVYRAS GKKQKSIFTS VPDTPDLLRA KRGQKLQSQY LYVELATKER PHHHAGNQTT 1680
ALQHAKDVKD MVSEKKYKIQ YEKMKDKYTP VADTPILIRA KRAYWNASDL RYKETFQKTK 1740
GRYHTVKDAL DIVYHRKVTD DISKVKYKEN YMSQLGIWSS IPDRPEHFHH RAVTDAVSDV 1800
KYKEDLTWLK GIGCYAYDTP DLTLAEQNKT LYSKYKYKEV FERTKSNFKY VADCPINRHF 1860
KYATQLMNEK KYRADYEQRK DKYHLVVDEP RHLLAKTAGD QISQIKYRKK YEKSKDKFTS 1920
VVDTPEHLRT TKVNKQISDI LYKLEYNKAR PRGYTTIHDT PMLLHVRKVK DEVSDLKYKE 1980
VYQRNKSNCT IKPDAVHIKA AKDAYKVNTN LDYKKQYEAN KAYWKWTPDR PDFIQAAKSS 2040
LQQSDFEYKL DREFLKGCKL SVTDDKDMVL ALRNSLIESD LKYKEKHVKE RGSCHAVPDT 2100
PQILLAKTVS NLVSENKYKD HVKKHLAQGS YTTLPETRDT VHVKAVTKHV SDTNYKKKFV 2160
KEKGKSNYSI MQEPPEVKHA MEVAKKQSDV AYKKDAKENL HYTTVADRPD IKKATQAAKQ 2220
ASEVEYRAKH RKEGSHGLSM LGRPDIEMAK KAAKLSSQVK YRENFDKEKG KTPKYNPKDS 2280
QLYKTMKDAN NLASEVKYKA DLKKLHKPVT DMKESLIMHH VLNTSQLASS YQYKKNYEKS 2340
KGHYHTIPDN LEQLHHREAT ELQSIVKYKE KYEKERGKPM LDFETPTYIT AKESQQMQSG 2400
KEYRKDYEES IKGRNLTGLE VTPALLHVRH ATKIASEKEY RKDLEESIRG RGLTEMEDTP 2460
DMLRAKNATQ ILNEKEYKRD LELEVKGRGL NAMANETPDF MRARNATDIA SQIKYKQSAE 2520
MEKANFTSVV DTPEIIHAQQ VKNLSSQKKY KEDAEKSMSY YETVLDTPEM QRVRENQKNF 2580
SLLQYQCDLK NSKGKITVVQ DTPEILRVKE NQKNFSSVLY KEDVSPGTAI GKTPEMLRVK 2640
QTQDHISSVK YKEAIGQGTP IPDLPEVKRV KETQKHISSV MYKENPGTGI PTTVTPEIER 2700
VKRNQENFSS VLYKESLGKG TPTAITPEME RVKRNQENFS SILYKENLSK GTPLPVTPEM 2760
ERAKRNQENF SSVLYSDSFR KQIQGKAAYV LDTPEMRRVR ETQRHISTVK YHEDFEKHKG 2820
CFTPVVTDPI TERVKKNTQD FSDINYRGIQ RKVVEMEQKR NDQDQDTITG LRVWRTNPGS 2880
VFDYDPAEDN IQSRSLHMIN VQAQRRSRDQ SRSASALSIS GGEEKSEHSE AADQRLSTYS 2940
DGGAFFSATS TAYKHVKTTQ LPQQRSSSVA TQQTTLSSIP SHPSTAGKIF RAIYDYIAAD 3000
ADEVSFKDGD AIVNAQAIDE GWMYGTVQRT GRTGMLPANY VEAI 3044 
Gene Ontology
 GO:0043234; C:protein complex; ISO:MGI.
 GO:0005865; C:striated muscle thin filament; TAS:MGI.
 GO:0030018; C:Z disc; IDA:MGI.
 GO:0030832; P:regulation of actin filament length; TAS:MGI.
 GO:0045214; P:sarcomere organization; TAS:MGI. 
Interpro
 IPR013998; Nebulin.
 IPR000900; Nebulin_35r-motif.
 IPR001452; SH3_domain. 
Pfam
 PF00880; Nebulin
 PF00018; SH3_1 
SMART
 SM00227; NEBU
 SM00326; SH3 
PROSITE
 PS51216; NEBULIN
 PS50002; SH3 
PRINTS
 PR00510; NEBULIN.