Tag | Content |
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CPLM ID | CPLM-005307 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Glutathione S-transferase kappa 1 |
Protein Synonyms/Alias | GST 13-13; GST class-kappa; GSTK1-1; rGSTK1; Glutathione S-transferase subunit 13 |
Gene Name | Gstk1 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
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36 | YQHLWNIKLKLRPAL | acetylation | [1] | 38 | HLWNIKLKLRPALLA | acetylation | [1] | 49 | ALLAGIMKDSGNQPP | acetylation | [1] | 68 | HKGQYILKEIPLLKQ | acetylation | [1] | 74 | LKEIPLLKQLFQVPM | acetylation | [1] | 85 | QVPMSVPKDFFGEHV | acetylation | [1] | 93 | DFFGEHVKKGTVNAM | acetylation | [1] | 116 | EQPEMLEKVSRELWM | acetylation | [1] | 158 | QAQHLLNKISTELVK | acetylation | [1] | 165 | KISTELVKSKLRETT | acetylation | [1] | 177 | ETTGAACKYGAFGLP | acetylation | [1] |
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Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Might confer protection against genotoxic and cytotoxic electrophiles in the mitochondrial compartment. |
Sequence Annotation | REGION 16 18 Glutathione binding. REGION 200 201 Glutathione binding. BINDING 53 53 Glutathione. BINDING 183 183 Glutathione; via amide nitrogen and MOD_RES 93 93 N6-acetyllysine (By similarity). |
Keyword | 3D-structure; Acetylation; Complete proteome; Direct protein sequencing; Mitochondrion; Reference proteome; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 226 AA |
Protein Sequence | MGPAPRVLEL FYDVLSPYSW LGFEVLCRYQ HLWNIKLKLR PALLAGIMKD SGNQPPAMVP 60 HKGQYILKEI PLLKQLFQVP MSVPKDFFGE HVKKGTVNAM RFLTAVSMEQ PEMLEKVSRE 120 LWMRIWSRDE DITESQNILS AAEKAGMATA QAQHLLNKIS TELVKSKLRE TTGAACKYGA 180 FGLPTTVAHV DGKTYMLFGS DRMELLAYLL GEKWMGPVPP TLNARL 226 |
Gene Ontology | GO:0005743; C:mitochondrial inner membrane; IEA:Compara. GO:0005759; C:mitochondrial matrix; IDA:HGNC. GO:0005777; C:peroxisome; IEA:Compara. GO:0004602; F:glutathione peroxidase activity; IEA:Compara. GO:0004364; F:glutathione transferase activity; IEA:EC. GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro. GO:0006749; P:glutathione metabolic process; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |