UniProt Accession

 ITM2A_MOUSE; Q61500; Q3TJP5; Q8K0H4; Q9CRW4 

Genbank Protein ID

 L38971; AF074020; AK014024; AK051956; AK167351; BC031420 

Genbank Nucleotide ID

 AAC37700.1; AAD14549.2; BAB29119.1; BAC34819.1; BAE39450.1; AAH31420.1 

Protein Name

 Integral membrane protein 2A 

Protein Synonyms/Alias

 Protein E25 

Gene Name

 Itm2a 

Gene Synonyms/Alias

 E25; Itm2 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
3	*****MVKIAFNTPT	ubiquitination	[1]
14	NTPTAVQKEEARQDV	ubiquitination	[1, 2]
37	RAQILTGKELRVVPQ	ubiquitination	[1, 2]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] BTB-ZF factors recruit the E3 ligase cullin 3 to regulate lymphoid effector programs.
 Mathew R, Seiler MP, Scanlon ST, Mao AP, Constantinides MG, Bertozzi-Villa C, Singer JD, Bendelac A.
 Nature. 2012 Nov 22;491(7425):618-21. [PMID: 23086144] 

Functional Description

  

Sequence Annotation

 DOMAIN 133 227 BRICHOS.
 CARBOHYD 166 166 N-linked (GlcNAc...) (Potential).  

Keyword

 Complete proteome; Glycoprotein; Membrane; Reference proteome; Signal-anchor; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 263 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. 

Interpro

 IPR007084; BRICHOS_dom. 

Pfam

 PF04089; BRICHOS 

SMART

 SM01039; BRICHOS 

PROSITE

 PS50869; BRICHOS 

PRINTS