CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-023381
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Probable maleylacetoacetate isomerase 1 
Protein Synonyms/Alias
 MAAI 1 
Gene Name
 CG9362 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
173RGFQGLEKVLSHSAGacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
  
Sequence Annotation
 DOMAIN 32 116 GST N-terminal.
 DOMAIN 121 241 GST C-terminal.
 REGION 42 47 Glutathione binding (By similarity).
 REGION 100 101 Glutathione binding (By similarity).
 REGION 144 146 Glutathione binding (By similarity).
 BINDING 88 88 Glutathione; via amide nitrogen and
 BINDING 140 140 Glutathione (By similarity).  
Keyword
 Complete proteome; Cytoplasm; Isomerase; Phenylalanine catabolism; Reference proteome; Tyrosine catabolism. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 246 AA 
Protein Sequence
MASATQLTHR GIHLAGLYRS SWSKPLFRHL ATKPILYSYW PSSCSWRVRV ALAIKKIDYD 60
IKPTSLLKTV SGHAYTDEYR EVNPMQKVPS LKIDGHTLCD SVAIIHYLEE TRPQPALLPQ 120
DPVKRAKIRE IVELICSGIQ PLQNVSVLDH IGKDQSLQWA QHWISRGFQG LEKVLSHSAG 180
KFCVGDELSM ADICLVPQVR NARRYKADLT PYPTIVRLNQ ELQELDVFKA THPSTQPDCP 240
PEFAKK 246 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0004364; F:glutathione transferase activity; IDA:FlyBase.
 GO:0016034; F:maleylacetoacetate isomerase activity; IEA:EC.
 GO:0006749; P:glutathione metabolic process; IDA:FlyBase.
 GO:0006559; P:L-phenylalanine catabolic process; IEA:UniProtKB-UniPathway.
 GO:0006572; P:tyrosine catabolic process; IEA:UniProtKB-KW. 
Interpro
 IPR010987; Glutathione-S-Trfase_C-like.
 IPR004045; Glutathione_S-Trfase_N.
 IPR017933; Glutathione_S_Trfase/Cl_chnl_C.
 IPR004046; GST_C.
 IPR005955; Mal_ac_isom.
 IPR012336; Thioredoxin-like_fold. 
Pfam
 PF00043; GST_C 
SMART
  
PROSITE
 PS50405; GST_CTER
 PS50404; GST_NTER 
PRINTS