Tag | Content |
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CPLM ID | CPLM-010669 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | GrpE protein homolog 1, mitochondrial |
Protein Synonyms/Alias | Mt-GrpE#1 |
Gene Name | Grpel1 |
Gene Synonyms/Alias | Grepel1 |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
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64 | DKTLLEEKVKLEEQL | acetylation | [1] | 66 | TLLEEKVKLEEQLKE | acetylation | [1] | 72 | VKLEEQLKETMEKYK | acetylation | [1] | 77 | QLKETMEKYKRALAD | acetylation | [1] | 94 | NLRQRSQKLVEEAKL | acetylation | [1] | 157 | QIQKVFTKHGLLRLD | acetylation | [1] | 186 | FHTPVEGKEPGTVAL | acetylation | [1] | 215 | PALVGVVKDA***** | acetylation | [1] |
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Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. |
Sequence Annotation | MOD_RES 215 215 N6-acetyllysine (By similarity). |
Keyword | Acetylation; Chaperone; Complete proteome; Direct protein sequencing; Mitochondrion; Reference proteome; Transit peptide. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 217 AA |
Protein Sequence | MAARCVRLAR RSLPALALSF RPSPRLLCTA TKQKNNGQNL EEDLGHCEPK TDPSSADKTL 60 LEEKVKLEEQ LKETMEKYKR ALADTENLRQ RSQKLVEEAK LYGIQGFCKD LLEVADILEK 120 ATQSVPKEEV SNNNPHLKSL YEGLVMTEVQ IQKVFTKHGL LRLDPIGAKF DPYEHEALFH 180 TPVEGKEPGT VALVSKVGYK LHGRTLRPAL VGVVKDA 217 |
Gene Ontology | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. GO:0000774; F:adenyl-nucleotide exchange factor activity; IEA:InterPro. GO:0006457; P:protein folding; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |