| Tag | Content |
|---|
| CPLM ID | CPLM-014489 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Nucleobindin-1 |
Protein Synonyms/Alias | Bone 63 kDa calcium-binding protein; CALNUC |
Gene Name | Nucb1 |
Gene Synonyms/Alias | Nuc |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 176 | AAHHEEFKRYEMLKE | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Major calcium-binding protein of the Golgi. May have a role in calcium homeostasis. |
Sequence Annotation | DOMAIN 239 274 EF-hand 1.
DOMAIN 291 326 EF-hand 2.
DNA_BIND 171 217 Potential.
REGION 227 320 Binds to GNAI2 and GNAI3.
MOD_RES 85 85 Phosphoserine (By similarity).
MOD_RES 368 368 Phosphoserine.
MOD_RES 456 456 Phosphoserine (By similarity). |
Keyword | Calcium; Coiled coil; Complete proteome; Cytoplasm; DNA-binding; Golgi apparatus; Membrane; Metal-binding; Phosphoprotein; Reference proteome; Repeat; Signal. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 459 AA |
Protein Sequence | MPTSVPRGAP FLLLPPLLML SAVLAVPVDR AAPHQEDNQA TETPDTGLYY HRYLQEVINV 60
LETDGHFREK LQAANAEDIK SGKLSQELDF VSHNVRTKLD ELKRQEVSRL RMLLKAKMDA 120
KQEPNLQVDH MNLLKQFEHL DPQNQHTFEA RDLELLIQTA TRDLAQYDAA HHEEFKRYEM 180
LKEHERRRYL ESLGEEQRKE AERKLQEQQR RHREHPKVNV PGSQAQLKEV WEELDGLDPN 240
RFNPKTFFIL HDINSDGVLD EQELEALFTK ELEKVYDPKN EEDDMREMEE ERLRMREHVM 300
KNVDTNQDRL VTLEEFLAST QRKEFGETAE GWKTVEMYPA YTEEELKRFE EELAAREAEL 360
NARAQRLSQE TEALGRSQDR LEAQKRELQQ AVLQMEQRKQ QQQEQSAPPS QPDGQLQFRA 420
DTGDAPVPAP AGDQKDVPAS EKKVPEQPPV LPQLDSQHL 459 |
Gene Ontology | GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; IEA:Compara. GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell. GO:0016020; C:membrane; IEA:UniProtKB-KW. GO:0015630; C:microtubule cytoskeleton; IEA:Compara. GO:0005509; F:calcium ion binding; IEA:InterPro. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |