CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036415
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Agl 
Protein Synonyms/Alias
  
Gene Name
 Agl 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
5***MEHSKQIRILLLacetylation[1, 2]
17LLLNEMEKLEKTLFRacetylation[1, 3]
17LLLNEMEKLEKTLFRubiquitination[4]
61GEAFNREKFRSLDWEubiquitination[4]
Reference
 [1] Quantitative assessment of the impact of the gut microbiota on lysine epsilon-acetylation of host proteins using gnotobiotic mice.
 Simon GM, Cheng J, Gordon JI.
 Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11133-8. [PMID: 22733758]
 [2] Circadian acetylome reveals regulation of mitochondrial metabolic pathways.
 Masri S, Patel VR, Eckel-Mahan KL, Peleg S, Forne I, Ladurner AG, Baldi P, Imhof A, Sassone-Corsi P.
 Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3339-44. [PMID: 23341599]
 [3] Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
 Rardin MJ, Newman JC, Held JM, Cusack MP, Sorensen DJ, Li B, Schilling B, Mooney SD, Kahn CR, Verdin E, Gibson BW.
 Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6. [PMID: 23576753]
 [4] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 117 AA 
Protein Sequence
MEHSKQIRIL LLNEMEKLEK TLFRLEQGFE LQFRLGPTLQ GKAVTVYTNY PLPGEAFNRE 60
KFRSLDWENP TEREDDSDKY CKLHLQQSGS FQYYFLQGNE KSGGGYIVVD PILRIGV 117 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:MGI.
 GO:0016234; C:inclusion body; IDA:MGI.
 GO:0005634; C:nucleus; IDA:MGI.
 GO:0016529; C:sarcoplasmic reticulum; IEA:Compara.
 GO:0004134; F:4-alpha-glucanotransferase activity; IBA:RefGenome.
 GO:0004135; F:amylo-alpha-1,6-glucosidase activity; IBA:RefGenome.
 GO:0030247; F:polysaccharide binding; IDA:MGI.
 GO:0031593; F:polyubiquitin binding; IDA:MGI.
 GO:0005978; P:glycogen biosynthetic process; IEA:InterPro.
 GO:0005980; P:glycogen catabolic process; IBA:RefGenome.
 GO:0051384; P:response to glucocorticoid stimulus; IEA:Compara.
 GO:0007584; P:response to nutrient; IEA:Compara. 
Interpro
 IPR010401; GDE_C. 
Pfam
  
SMART
  
PROSITE
  
PRINTS