UniProt Accession

 EMC3_MOUSE; Q99KI3; Q3TIK3 

Genbank Protein ID

 AK075595; AK167819; BC004641 

Genbank Nucleotide ID

 BAC35844.1; BAE39843.1; AAH04641.1 

Protein Name

 ER membrane protein complex subunit 3 

Protein Synonyms/Alias

 Transmembrane protein 111 

Gene Name

 Emc3 

Gene Synonyms/Alias

 Tmem111 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
66	RVLRENGKYIPKQSF	ubiquitination	[1]
94	FFKKTKRKVVPPSPM	ubiquitination	[1]
216	AMPADTNKAFKTEWE	ubiquitination	[1]
253	LHFEGMFKKELQTSI	acetylation	[2]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 261 AA 

Protein Sequence

Gene Ontology

 GO:0072546; C:ER membrane protein complex; ISS:UniProtKB. 

Interpro

 IPR002809; DUF106_TM.
 IPR008568; UCP010045_TM_euk. 

Pfam

 PF01956; DUF106 

SMART

  

PROSITE

  

PRINTS