UniProt Accession

 FRIL1_MOUSE; P29391; Q8WUQ8 

Genbank Protein ID

 J04716; L39879; BC019840 

Genbank Nucleotide ID

 AAA37614.1; AAA62259.1; AAH19840.1 

Protein Name

 Ferritin light chain 1 

Protein Synonyms/Alias

 Ferritin L subunit 1 

Gene Name

 Ftl1 

Gene Synonyms/Alias

 Ftl; Ftl-1 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
84	ALFQDVQKPSQDEWG	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney. 

Sequence Annotation

 DOMAIN 7 156 Ferritin-like diiron.
 METAL 54 54 Iron (Potential).
 METAL 57 57 Iron (Potential).
 METAL 58 58 Iron (Potential).
 METAL 61 61 Iron (Potential).
 METAL 64 64 Iron (Potential).  

Keyword

 3D-structure; Complete proteome; Direct protein sequencing; Iron; Iron storage; Metal-binding; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 183 AA 

Protein Sequence

Gene Ontology

 GO:0008043; C:intracellular ferritin complex; ISS:UniProtKB.
 GO:0008199; F:ferric iron binding; IEA:InterPro.
 GO:0005506; F:iron ion binding; ISS:UniProtKB.
 GO:0016491; F:oxidoreductase activity; IEA:InterPro.
 GO:0006879; P:cellular iron ion homeostasis; IEA:UniProtKB-KW.
 GO:0006826; P:iron ion transport; IEA:InterPro. 

Interpro

 IPR001519; Ferritin.
 IPR009040; Ferritin-like_diiron.
 IPR009078; Ferritin-like_SF.
 IPR012347; Ferritin-rel.
 IPR014034; Ferritin_CS.
 IPR008331; Ferritin_DPS_dom. 

Pfam

 PF00210; Ferritin 

SMART

  

PROSITE

 PS00540; FERRITIN_1
 PS00204; FERRITIN_2
 PS50905; FERRITIN_LIKE 

PRINTS