UniProt Accession

 GALT_HUMAN; P07902; B4E097; E7ET32; Q14355; Q14356; Q14357; Q14358; Q14359; Q14360; Q14361; Q14363; Q14364; Q14365; Q14369; Q14370; Q14371; Q14372; Q14373; Q14374; Q14375; Q14377; Q14378; Q14380; Q14381; Q14382; Q14383; Q14384; Q14385; Q14386; Q14387; Q14389; Q16766; Q53XK1; Q5VZ81; Q96BY1 

Genbank Protein ID

 M60091; M96264; L46359; L46360; L46361; L46362; L46363; L46364; L46365; L46691; L46692; L46693; L46694; L46698; L46699; L46703; L46704; L46705; L46706; L46707; L46708; L46709; L46710; L46711; L46712; L46713; L46714; L46715; L46716; L46717; BT009852; AK303279; AL162231; AL450283; CH471071; BC015045 

Genbank Nucleotide ID

 AAC83409.1; AAA74450.1; AAB59606.1; AAB59604.1; AAB59605.1; AAB59603.1; AAB59607.1; AAB59584.1; AAB59585.1; AAB59586.1; AAB59588.1; AAB59587.1; AAB59589.1; AAB59590.1; AAB59608.1; AAB59591.1; AAB59578.1; AAB59592.1; AAB59593.1; AAA81544.1; AAA81545.1; AAB59594.1; AAB59595.1; AAB59596.1; AAB59597.1; AAB59598.1; AAB59599.1; AAB59601.1; AAB59600.1; AAA81546.1; AAP88854.1; BAG64359.1; CAH69856.1; EAW58428.1; AAH15045.1 

Protein Name

 Galactose-1-phosphate uridylyltransferase 

Protein Synonyms/Alias

 Gal-1-P uridylyltransferase; UDP-glucose--hexose-1-phosphate uridylyltransferase 

Gene Name

 GALT 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
120	DHPLFQAKSARGVCK	ubiquitination	[1]
210	ERSQQAYKSQHGEPL	ubiquitination	[2]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

 ACT_SITE 186 186 Tele-UMP-histidine intermediate (By
 METAL 75 75 Zinc (Potential).
 METAL 184 184 Zinc (Potential).
 METAL 202 202 Iron (Potential).
 METAL 301 301 Iron (Potential).
 METAL 319 319 Iron (Potential).
 METAL 321 321 Iron (Potential).  

Keyword

 3D-structure; Alternative splicing; Carbohydrate metabolism; Cataract; Complete proteome; Disease mutation; Galactose metabolism; Iron; Metal-binding; Nucleotidyltransferase; Polymorphism; Reference proteome; Transferase; Zinc. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 379 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; TAS:Reactome.
 GO:0005794; C:Golgi apparatus; IDA:UniProtKB.
 GO:0008108; F:UDP-glucose:hexose-1-phosphate uridylyltransferase activity; IEA:EC.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0019388; P:galactose catabolic process; TAS:Reactome.
 GO:0044281; P:small molecule metabolic process; TAS:Reactome.
 GO:0006258; P:UDP-glucose catabolic process; IEA:Compara. 

Interpro

 IPR001937; GalP_UDPtransf1.
 IPR019779; GalP_UDPtransf1_His-AS.
 IPR005850; GalP_Utransf_C.
 IPR005849; GalP_Utransf_N.
 IPR011146; HIT-like. 

Pfam

 PF02744; GalP_UDP_tr_C
 PF01087; GalP_UDP_transf 

SMART

  

PROSITE

 PS00117; GAL_P_UDP_TRANSF_I 

PRINTS