CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028754
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Cystatin-C 
Protein Synonyms/Alias
  
Gene Name
 Cst3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
56FAVSEYNKGSNDAYHubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Protease inhibitor; Reference proteome; Thiol protease inhibitor. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 102 AA 
Protein Sequence
MASPLRSLLF LLAVLAVAWA ATPKQGPRML GAPEEADANE EGVRRALDFA VSEYNKGSND 60
AYHSRAIQVV RARKQLVAGV NYFLDVEMGR TTCTKSQTNL TD 102 
Gene Ontology
 GO:0005604; C:basement membrane; IEA:Compara.
 GO:0042995; C:cell projection; IEA:Compara.
 GO:0043292; C:contractile fiber; IEA:Compara.
 GO:0005783; C:endoplasmic reticulum; IEA:Compara.
 GO:0005615; C:extracellular space; IEA:Compara.
 GO:0005764; C:lysosome; IEA:Compara.
 GO:0005771; C:multivesicular body; IEA:Compara.
 GO:0043025; C:neuronal cell body; IEA:Compara.
 GO:0031965; C:nuclear membrane; IEA:Compara.
 GO:0048471; C:perinuclear region of cytoplasm; IEA:Compara.
 GO:0031982; C:vesicle; IEA:Compara.
 GO:0001540; F:beta-amyloid binding; IEA:Compara.
 GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
 GO:0006915; P:apoptotic process; IEA:Compara.
 GO:0007420; P:brain development; IEA:Compara.
 GO:0001775; P:cell activation; IEA:Compara.
 GO:0070301; P:cellular response to hydrogen peroxide; IEA:Compara.
 GO:0042747; P:circadian sleep/wake cycle, REM sleep; IEA:Compara.
 GO:0006952; P:defense response; IEA:Compara.
 GO:0007566; P:embryo implantation; IEA:Compara.
 GO:0043206; P:extracellular fibril organization; IEA:Compara.
 GO:0001654; P:eye development; IEA:Compara.
 GO:0060313; P:negative regulation of blood vessel remodeling; IEA:Compara.
 GO:0060548; P:negative regulation of cell death; IEA:Compara.
 GO:0010711; P:negative regulation of collagen catabolic process; IEA:Compara.
 GO:0060311; P:negative regulation of elastin catabolic process; IEA:Compara.
 GO:0010716; P:negative regulation of extracellular matrix disassembly; IEA:Compara.
 GO:0008284; P:positive regulation of cell proliferation; IEA:Compara.
 GO:0045740; P:positive regulation of DNA replication; IEA:Compara.
 GO:0043067; P:regulation of programmed cell death; IEA:Compara.
 GO:0048678; P:response to axon injury; IEA:Compara.
 GO:0009743; P:response to carbohydrate stimulus; IEA:Compara.
 GO:0042493; P:response to drug; IEA:Compara.
 GO:0032355; P:response to estradiol stimulus; IEA:Compara.
 GO:0001666; P:response to hypoxia; IEA:Compara.
 GO:0031667; P:response to nutrient levels; IEA:Compara.
 GO:0009636; P:response to toxic substance; IEA:Compara.
 GO:0007431; P:salivary gland development; IEA:Compara.
 GO:0060009; P:Sertoli cell development; IEA:Compara. 
Interpro
 IPR027214; Cystatin.
 IPR000010; Prot_inh_cystat.
 IPR018073; Prot_inh_cystat_CS. 
Pfam
 PF00031; Cystatin 
SMART
 SM00043; CY 
PROSITE
 PS00287; CYSTATIN 
PRINTS