UniProt Accession

 A8MX62_HUMAN; A8MX62 

Genbank Protein ID

 AC002456; AC006153 

Genbank Nucleotide ID

  

Protein Name

 Claudin-12 

Protein Synonyms/Alias

  

Gene Name

 CLDN12 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
121	RSSVPNIKLAKCLVN	ubiquitination	[1, 2]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 187 AA 

Protein Sequence

Gene Ontology

 GO:0071944; C:cell periphery; IEA:Compara.
 GO:0005923; C:tight junction; IEA:InterPro.
 GO:0005198; F:structural molecule activity; IEA:InterPro. 

Interpro

 IPR013287; Claudin12.
 IPR017974; Claudin_CS. 

Pfam

  

SMART

  

PROSITE

 PS01346; CLAUDIN 

PRINTS

 PR01872; CLAUDIN12.