CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040358
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Glutamate receptor 1 
Protein Synonyms/Alias
  
Gene Name
 Gria1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
289GNVQFNEKGRRTNYTubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Cell junction; Cell membrane; Complete proteome; Ion channel; Ion transport; Ligand-gated ion channel; Membrane; Postsynaptic cell membrane; Receptor; Reference proteome; Synapse; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 838 AA 
Protein Sequence
MTYRFCSQFS KGVYAIFGFY ERRTVNMLTS FCGALHVCFI TPSFPVDTSN QFVLQLRPEL 60
QEALISIIDH YKWQTFVYIY DADRGLSVLQ RVLDTAAEKN WQVTAVNILT TTEEGYRMLF 120
QDLEKKKERL VVVDCESERL NAILGQIVKL EKNGIGYHYI LANLGFMDID LNKFKESGAN 180
VTGFQLVNYT DTIPARIMQQ WRTSDARDHT RVDWKRPKYT SALTYDGVKV MAEAFQSLRR 240
QRIDISRRGN AGDCLANPAV PWGQGIDIQR ALQQVRFEGL TGNVQFNEKG RRTNYTLHVI 300
EMKHDGIRKI GYWNEDDKFV PAATDAQAGG DNSSVQNRTY IVTTILEDPY VMLKKNANQF 360
EGNDRYEGYC VELAAEIAKH VGYSYRLEIV SDGKYGARDP DTKAWNGMVG ELVYGRADVA 420
VAPLTITLVR EEVIDFSKPF MSLGISIMIK KPQKSKPGVF SFLDPLAYEI WMCIVFAYIG 480
VSVVLFLVSR FSPYEWHSEE FEEGRDQTTS DQSNEFGIFN SLWFSLGAFM QQGCDISPRS 540
LSGRIVGGVW WFFTLIIISS YTANLAAFLT VERMVSPIES AEDLAKQTEI AYGTLEAGST 600
KEFFRRSKIA VFEKMWTYMK SAEPSVFVRT TEEGMIRVRK SKGKYAYLLE STMNEYIEQR 660
KPCDTMKVGG NLDSKGYGIA TPKGSALRGP VNLAVLKLSE QGVLDKLKSK WWYDKGECGS 720
KDSGSKDKTS ALSLSNVAGV FYILIGGLGL AMLVALIEFC YKSRSESKRM KGFCLIPQQS 780
INEAIRTSTL PRNSGAGASG GSGSGENGRV VSQDFPKSMQ SIPCMSHSSG MPLGATGL 838 
Gene Ontology
 GO:0032281; C:alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex; IDA:MGI.
 GO:0030054; C:cell junction; IEA:UniProtKB-KW.
 GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
 GO:0008021; C:synaptic vesicle; IDA:MGI.
 GO:0005234; F:extracellular-glutamate-gated ion channel activity; IEA:InterPro.
 GO:0004970; F:ionotropic glutamate receptor activity; IEA:InterPro.
 GO:0035235; P:ionotropic glutamate receptor signaling pathway; IEA:GOC.
 GO:0007268; P:synaptic transmission; IGI:MGI. 
Interpro
 IPR001828; ANF_lig-bd_rcpt.
 IPR019594; Glu_rcpt_Glu/Gly-bd.
 IPR001320; Iontro_glu_rcpt.
 IPR001508; NMDA_rcpt. 
Pfam
 PF01094; ANF_receptor
 PF00060; Lig_chan
 PF10613; Lig_chan-Glu_bd 
SMART
 SM00918; Lig_chan-Glu_bd
 SM00079; PBPe 
PROSITE
  
PRINTS
 PR00177; NMDARECEPTOR.