CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020590
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Methylsterol monooxygenase 1 
Protein Synonyms/Alias
 C-4 methylsterol oxidase 
Gene Name
 Msmo1 
Gene Synonyms/Alias
 Sc4mol 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
85MRKYKIQKDKPETFEubiquitination[1]
284QYHAYIEKSKKLGKKubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
 MOTIF 157 161 Histidine box-1.
 MOTIF 170 174 Histidine box-2.
 MOTIF 249 255 Histidine box-3.  
Keyword
 Complete proteome; Endoplasmic reticulum; Iron; Lipid biosynthesis; Lipid metabolism; Membrane; NAD; Oxidoreductase; Reference proteome; Steroid biosynthesis; Steroid metabolism; Sterol biosynthesis; Sterol metabolism; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 293 AA 
Protein Sequence
MATNKSVGVF SSASLAVEYV DSLLPENPLQ EPFKNAWVYM LDNYTKFQIA TWGSLIVHEA 60
IYFLFSLPGF LFQFIPYMRK YKIQKDKPET FEGQWKCLKK ILFNHFFIQL PLICGTYYFT 120
EFFNIPYDWE RMPRWYLTLA RCLGCAVIED TWHYFLHRLL HHKRIYKYIH KVHHEFQAPF 180
GIEAEYAHPL ETLILGTGFF IGIVLLCDHV ILLWAWVTIR LLETIDVHSG YDIPLNPLNL 240
VPFYTGARHH DFHHMNFIGN YASTFTWWDK LFGTDAQYHA YIEKSKKLGK KSD 293 
Gene Ontology
 GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0000254; F:C-4 methylsterol oxidase activity; IEA:EC.
 GO:0005506; F:iron ion binding; IEA:InterPro.
 GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
 GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. 
Interpro
 IPR006694; Fatty_acid_hydroxylase. 
Pfam
 PF04116; FA_hydroxylase 
SMART
  
PROSITE
  
PRINTS