CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038899
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Neural cell adhesion molecule 1 
Protein Synonyms/Alias
  
Gene Name
 Ncam1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
637PIRHYLVKYRALASEacetylation[1]
646RALASEWKPEIRLPSacetylation[1]
683ENQQGKSKAAHFVFRacetylation[1]
759AGPGAKGKDMEEGKAubiquitination[2]
765GKDMEEGKAAFSKDEubiquitination[2]
774AFSKDESKEPIVEVRubiquitination[2]
809TPLTEPEKGPVETKSubiquitination[2]
815EKGPVETKSEPQESEubiquitination[2]
824EPQESEAKPAPTEVKubiquitination[2]
841PNEATQTKENESKA*ubiquitination[2]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 847 AA 
Protein Sequence
FFFSFAVSLQ VDIVPSQGEI SVGESKFFLC QVAGDAKDKD ISWFSPNGEK LSPNQQRISV 60
VWNDDDSSTL TIYNANIDDA GIYKCVVTAE DGTQSEATVN VKIFQKLMFK NAPTPQEFKE 120
GEDAVIVCDV VSSLPPTIIW KHKGRDVILK KDVRFIVLSN NYLQIRGIKK TDEGTYRCEG 180
RILARGEINF KDIQVIVNVP PTVQARQSIV NATANLGQSV TLVCDADGFP EPTMSWTKDG 240
EPIENEEEDD EKHIFSDDSS ELTIRNVDKN DEAEYVCIAE NKAGEQDASI HLKVFAKPKI 300
TYVENQTAME LEEQVTLTCE ASGDPIPSIT WRTSTRNISS EEKASWTRPE KQETLDGHMV 360
VRSHARVSSL TLKSIQYTDA GEYICTASNT IGQDSQSMYL EVQYAPKLQG PVAVYTWEGN 420
QVNITCEVFA YPSATISWFR DGQLLPSSNY SNIKIYNTPS ASYLEVTPDS ENDFGNYNCT 480
AVNRIGQESL EFILVQADTP SSPSIDRVEP YSSTAQVQFD EPEATGGVPI LKYKAEWKSL 540
GEEAWHSKWY DAKEANMEGI VTIMGLKPET RYAVRLAALN GKGLGEISAA TEFKTQPVRE 600
PSAPKLEGQM GEDGNSIKVN LIKQDDGGSP IRHYLVKYRA LASEWKPEIR LPSGSDHVML 660
KSLDWNAEYE VYVVAENQQG KSKAAHFVFR TSAQPTAIPA NGSPTAGLST GAIVGILIVI 720
FVLLLVVMDI TCYFLNKCGL LMCIAVNLCG KAGPGAKGKD MEEGKAAFSK DESKEPIVEV 780
RTEEERTPNH DGGKHTEPNE TTPLTEPEKG PVETKSEPQE SEAKPAPTEV KTVPNEATQT 840
KENESKA 847 
Gene Ontology
 GO:0030424; C:axon; IEA:Compara.
 GO:0009897; C:external side of plasma membrane; IEA:Compara.
 GO:0030426; C:growth cone; IEA:Compara.
 GO:0043025; C:neuronal cell body; IEA:Compara.
 GO:0007166; P:cell surface receptor signaling pathway; IEA:Compara.
 GO:0034109; P:homotypic cell-cell adhesion; IEA:Compara.
 GO:0031175; P:neuron projection development; IEA:Compara.
 GO:0050850; P:positive regulation of calcium-mediated signaling; IEA:Compara.
 GO:0001928; P:regulation of exocyst assembly; IEA:Compara. 
Interpro
 IPR003961; Fibronectin_type3.
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR013098; Ig_I-set.
 IPR003598; Ig_sub2.
 IPR009138; Neural_cell_adh. 
Pfam
 PF00041; fn3
 PF07679; I-set 
SMART
 SM00060; FN3
 SM00408; IGc2 
PROSITE
 PS50853; FN3
 PS50835; IG_LIKE 
PRINTS
 PR01838; NCAMFAMILY.