UniProt Accession

 GBG12_MOUSE; Q9DAS9; Q544P3 

Genbank Protein ID

 AK005561; AK033422; AK148765; AK159872; AK162342; AK166035; AK166299; BC040685 

Genbank Nucleotide ID

 BAB24121.1; BAC28280.1; BAE28660.1; BAE35445.1; BAE36863.1; BAE38536.1; BAE38688.1; AAH40685.1 

Protein Name

 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 

Protein Synonyms/Alias

  

Gene Name

 Gng12 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
4	****MSSKTASTNSI	acetylation	[1]
4	****MSSKTASTNSI	succinylation	[1]
4	****MSSKTASTNSI	ubiquitination	[2]
34	IERIKVSKASADLMS	ubiquitination	[2]
64	PTSENPFKDKKTCII	ubiquitination	[2]

Reference

 [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. 

Sequence Annotation

 MOD_RES 2 2 N-acetylserine (By similarity).
 MOD_RES 10 10 Phosphoserine.
 MOD_RES 26 26 Phosphoserine.
 MOD_RES 69 69 Cysteine methyl ester (By similarity).
 LIPID 69 69 S-geranylgeranyl cysteine (By  

Keyword

 Acetylation; Cell membrane; Complete proteome; Lipoprotein; Membrane; Methylation; Phosphoprotein; Prenylation; Reference proteome; Transducer. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 72 AA 

Protein Sequence

Gene Ontology

 GO:0005834; C:heterotrimeric G-protein complex; IEA:InterPro.
 GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
 GO:0007186; P:G-protein coupled receptor signaling pathway; IEA:InterPro. 

Interpro

 IPR015898; G-protein_gamma-like_dom.
 IPR001770; Gprotein-gamma. 

Pfam

 PF00631; G-gamma 

SMART

 SM00224; GGL 

PROSITE

 PS50058; G_PROTEIN_GAMMA 

PRINTS

 PR00321; GPROTEING.