CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013829
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Mitochondrial enolase superfamily member 1 
Protein Synonyms/Alias
  
Gene Name
 ENOSF1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) 
NCBI Taxa ID
 9601 
Lysine Modification
Position
Peptide
Type
References
292LGHATISKALVPLGIubiquitination[1]
314CHNRVIFKQLLQAKAubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
 May regulate thymidylate synthase activity (By similarity). 
Sequence Annotation
 ACT_SITE 222 222 By similarity.
 ACT_SITE 355 355 By similarity.
 METAL 250 250 Magnesium (By similarity).
 METAL 276 276 Magnesium (By similarity).
 METAL 305 305 Magnesium (By similarity).
 MOD_RES 148 148 Phosphoserine (By similarity).  
Keyword
 Complete proteome; Isomerase; Magnesium; Metal-binding; Mitochondrion; Phosphoprotein; Reference proteome; Ubl conjugation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 443 AA 
Protein Sequence
MVRGRIFRLS VRDVRFPTSL GGHGSDAMHT DPDYSAAYVV IETDAEDGIK GCGITFTLGK 60
GTEVVVCAVN ALAHHVLNKD LKDIVGDFRG FYRQLTSDGQ PRWIGPEKGV VHLATAAVLN 120
AVWDLWAKQE GKPVWKLLVD MDPRTLVSCI DFRYITDVLT EEDALEILQK GQVGKKEREK 180
QMLAQGYPAY TTSCAWLGYS DDTLKQLCAQ ALKDGWTRFK VKVGADLQDD VRRCQIIRDM 240
IGLEKTLMMD ANQRWDVPEA VEWMSKLAKF KPLWIEEPTS PDDILGHATI SKALVPLGIG 300
IATGEQCHNR VIFKQLLQAK ALQFLQIDSC RLGSVNENLS VLLMAKKFEI PVCPHAGGVG 360
LCELVQHLII FDYISVSASL ENRMCEYVDH LHEHFKYPVM IQRASYMPPK DPGYSTEMKE 420
ESVKKHQYPD GEVWKKLLAA QEN 443 
Gene Ontology
 GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
 GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0009063; P:cellular amino acid catabolic process; IEA:InterPro. 
Interpro
 IPR018110; Mandel_Rmase/mucon_lact_enz_CS.
 IPR013342; Mandelate_racemase_C.
 IPR013341; Mandelate_racemase_N.
 IPR001354; MR_MLE. 
Pfam
 PF01188; MR_MLE
 PF02746; MR_MLE_N 
SMART
 SM00922; MR_MLE 
PROSITE
 PS00908; MR_MLE_1
 PS00909; MR_MLE_2 
PRINTS