CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043635
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein timeless homolog 
Protein Synonyms/Alias
  
Gene Name
 Timeless 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
288SYIVQGLKSIGEKDVacetylation[1]
299EKDVVFHKGLHNLQNacetylation[1]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 534 AA 
Protein Sequence
MDLYMMNCEL LATCSALGYL EGGTYHKEPD CLESVKDLIR YLRHEDETRD VRQQLGAAQI 60
LQSDLLPILT QHRQDKPLFD AVIRLMVNLT QPALLCFGSV PKDSSVRHHF LQVLTYLQAY 120
KEAFASEKAF GVLSETLYEL LQLGWEDRQE EDNLLIERIL LLVRNILHVP ANLEQEKSID 180
DDASIHDRLL WAIHLSGMDD LLLFLSSSSA EQQWSLHVLE IISLMFRDQT PEQLAGVGQG 240
RLAQERSTDV AELEVLRQRE MAEKRARALQ RGNRHSRFGG SYIVQGLKSI GEKDVVFHKG 300
LHNLQNYSSD LGKQPRRVPK RRQAAQELSV HRRSVLNVRL FLRDFCSEFL ENCYNPLMGA 360
VKDHLLRERA QQHDETYYMW AMAFFMAFNR AATFRPGLVS ETLSIRTFHF VEQNLTNYYE 420
MMLTDRKEAA SWARRMHLAL KAYQELLATV NEMDMCPDEA VRESSRIIKN NIFYMMEYRE 480
LFLALFRKFD ERYHPRSFLR DLVETTHLFL KMLERFCRSR GNLMVQNKRK KRKK 534 
Gene Ontology
 GO:0000790; C:nuclear chromatin; IEA:Compara.
 GO:0005634; C:nucleus; IDA:MGI.
 GO:0042803; F:protein homodimerization activity; IDA:MGI.
 GO:0048754; P:branching morphogenesis of an epithelial tube; IMP:MGI.
 GO:0009790; P:embryo development; IMP:MGI.
 GO:0030324; P:lung development; IMP:MGI.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.
 GO:0033261; P:regulation of S phase; IEA:Compara. 
Interpro
 IPR006906; Timeless. 
Pfam
 PF04821; TIMELESS 
SMART
  
PROSITE
  
PRINTS