CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032433
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial 
Protein Synonyms/Alias
  
Gene Name
 HIBCH 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
29ENYHTESKIDRDKSFubiquitination[1]
130VRAVLIDKDQSPKWKacetylation[2, 3, 4]
Reference
 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [2] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773]
 [3] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [4] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 163 AA 
Protein Sequence
MLEEDLLALK SPSKENIASV LENYHTESKI DRDKSFILEE HMDKINSCFS ANTVEEIIEN 60
LQQDGSSFAL EQLKVINKMS PTSLKITLRQ LMEGSSKTLQ EVLTMEYRLS QACMRGHDFH 120
EGVRAVLIDK DQSPKWKPAD LKEVTEEDLN NHFKSLGSSD LKF 163 
Gene Ontology
 GO:0005739; C:mitochondrion; IEA:Compara. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS