CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037831
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Anoctamin 
Protein Synonyms/Alias
  
Gene Name
 ANO1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
34NVEFNDRKLLYEEWAubiquitination[1]
48ARYGVFYKYQPIDLVubiquitination[1]
186EEEEEAVKDHPRAEYubiquitination[2]
301CIARWLTKIEVPKTEubiquitination[1]
490RPVAVRAKDIGIWYNubiquitination[1]
650FMREEQDKQQLLETWubiquitination[1, 2]
660LLETWMEKERQKDEPubiquitination[1, 2]
Reference
 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 695 AA 
Protein Sequence
MGITSLLANG VYAAAYPLHD GDYNGENVEF NDRKLLYEEW ARYGVFYKYQ PIDLVRKYFG 60
EKIGLYFAWL GVYTQMLIPA SIVGIIVFLY GCATMDENIP SMEMCDQRHN ITMCPLCDKT 120
CSYWKMSSAC ATARASHLFD NPATVFFSVF MALWAATFME HWKRKQMRLN YRWDLTGFEE 180
EEEAVKDHPR AEYEARVLEK SLKKESRNKE TDKVKLTWRD RFPAYLTNLV SIIFMIAVTF 240
AIVLGVIIYR ISMAAALAMN SSPSVRSNIR VTVTATAVII NLVVIILLDE VYGCIARWLT 300
KIEVPKTEKS FEERLIFKAF LLKFVNSYTP IFYVAFFKGR FVGRPGDYVY IFRSFRMEEC 360
APGGCLMELC IQLSIIMLGK QLIQNNLFEI GIPKMKKLIR YLKLKQQSPP DHEECVKRKQ 420
RYEVDYNLEP FAGLTPEYME MIIQFGFVTL FVASFPLAPL FALLNNIIEI RLDAKKFVTE 480
LRRPVAVRAK DIGIWYNILR GIGKLAVIIN AFVISFTSDF IPRLVYLYMY SKNGTMHGFV 540
NHTLSSFNVS DFQNGTAPND PLDLGYEVQI CRYKDYREPP WSENKYDISK DFWAVLAARL 600
AFVIVFQNLV MFMSDFVDWV IPDIPKDISQ QIHKEKVLMV ELFMREEQDK QQLLETWMEK 660
ERQKDEPPCN HHNTKACPDS LGSPAPSHAY HGGVL 695 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. 
Interpro
 IPR007632; Anoctamin. 
Pfam
 PF04547; Anoctamin 
SMART
  
PROSITE
  
PRINTS