CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-008473
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transcriptional regulatory protein RstA 
Protein Synonyms/Alias
  
Gene Name
 rstA 
Gene Synonyms/Alias
 urpT; b1608; JW1600 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
137ETSLTPYKALHFGTLacetylation[1]
211VAISRLRKKLLDNAAacetylation[1]
212AISRLRKKLLDNAAEacetylation[1]
229RIKTVRNKGYLFAPHacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
 Member of the two-component regulatory system RstB/RstA. 
Sequence Annotation
 DOMAIN 3 116 Response regulatory.
 MOD_RES 52 52 4-aspartylphosphate (By similarity).  
Keyword
 Complete proteome; Cytoplasm; DNA-binding; Phosphoprotein; Reference proteome; Transcription; Transcription regulation; Two-component regulatory system. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 239 AA 
Protein Sequence
MNTIVFVEDD AEVGSLIAAY LAKHDMQVTV EPRGDQAEET ILRENPDLVL LDIMLPGKDG 60
MTICRDLRAK WSGPIVLLTS LDSDMNHILA LEMGACDYIL KTTPPAVLLA RLRLHLRQNE 120
QATLTKGLQE TSLTPYKALH FGTLTIDPIN RVVTLANTEI SLSTADFELL WELATHAGQI 180
MDRDALLKNL RGVSYDGLDR SVDVAISRLR KKLLDNAAEP YRIKTVRNKG YLFAPHAWE 239 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0000156; F:phosphorelay response regulator activity; IEA:InterPro.
 GO:0035556; P:intracellular signal transduction; IEA:GOC.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR011006; CheY-like_superfamily.
 IPR001867; Sig_transdc_resp-reg_C.
 IPR016032; Sig_transdc_resp-reg_C-effctor.
 IPR001789; Sig_transdc_resp-reg_receiver.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF00072; Response_reg
 PF00486; Trans_reg_C 
SMART
 SM00448; REC
 SM00862; Trans_reg_C 
PROSITE
 PS50110; RESPONSE_REGULATORY 
PRINTS