CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027570
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Purine nucleoside phosphorylase 
Protein Synonyms/Alias
 Inosine-guanosine phosphorylase 
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
22EWLLSHTKHRPQVAIubiquitination[1]
183QRALSTWKQMGEQREubiquitination[1]
Reference
 [1] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 
Functional Description
 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity). 
Sequence Annotation
  
Keyword
 Glycosyltransferase; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 293 AA 
Protein Sequence
MENGYTYEDY KNTAEWLLSH TKHRPQVAII CGSGLGGLTD KLTQAQIFDY GEIPNFPRST 60
VPGHAGRLVF GFLNGRACVM MQGRFHMYEG YPLWKFASKV TFPVRVFHLL GVDTLVVTNA 120
AGGLNPKFEV GDIMLIRDHI NLPGFSGQNP LRGPNDERFG DRFPAMSDAY DRTMRQRALS 180
TWKQMGEQRE LQEGTYVMVA GPSFETVAEC RVLQKLGADA VGMSTVPEVI VARHCGLRVF 240
GFSLITNKVI MDYESLEKAN HEEVLAAGKQ AAQKLEQFVS ILMASIPLPD KAS 293 
Gene Ontology
 GO:0004731; F:purine-nucleoside phosphorylase activity; IEA:EC.
 GO:0009116; P:nucleoside metabolic process; IEA:InterPro. 
Interpro
 IPR000845; Nucleoside_phosphorylase_d.
 IPR001369; PNP/MTAP.
 IPR011270; Pur_Nuc_Pase_Ino/Guo-sp.
 IPR011268; Purine_phosphorylase. 
Pfam
 PF01048; PNP_UDP_1 
SMART
  
PROSITE
  
PRINTS