CPLM 1.0 - Compendium of Protein Lysine Modification
Tag
Content
CPLM ID
CPLM-025613
UniProt Accession
Q4LE27_HUMAN
;
Q4LE27
Genbank Protein ID
AB210044
Genbank Nucleotide ID
BAE06126.1
Protein Name
ABCA3 variant protein
Protein Synonyms/Alias
Gene Name
ABCA3 variant protein
Gene Synonyms/Alias
Created Date
July 27, 2013
Organism
Homo sapiens (Human)
NCBI Taxa ID
9606
Lysine Modification
Position
Peptide
Type
References
1388
LHTPLII
K
ELSKVYE
ubiquitination
[1]
1672
KVFGILE
K
AKEKYGV
ubiquitination
[1]
Reference
[1] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
Chen Z, Zhou Y, Song J, Zhang Z.
Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [
PMID: 23603789
]
Functional Description
Sequence Annotation
Keyword
ATP-binding; Nucleotide-binding.
Sequence Source
UniProt (SWISSPROT/TrEMBL); GenBank; EMBL
Protein Length
1708 AA
Protein Sequence
TAPPPSPSLP LQDRAATSAH LALFTLSFQS TFLLFPAGCS AYLNLLRPPT SLAALGVPFS 60
KTMAVLRQLA LLLWKNYTLQ KRKVLVTVLE LFLPLLFSGI LIWLRLKIQS ENVPNATIYP 120
GQSIQELPLF FTFPPPGDTW ELAYIPSHSD AAKTVTETVR RALVINMRVR GFPSEKDFED 180
YIRYDNCSSS VLAAVVFEHP FNHSKEPLPL AVKYHLRFSY TRRNYMWTQT GSFFLKETEG 240
WHTTSLFPLF PNPGPREPTS PDGGEPGYIR EGFLAVQHAV DRAIMEYHAD AATRQLFQRL 300
TVTIKRFPYP PFIADPFLVA IQYQLPLLLL LSFTYTALTI ARAVVQEKER RLKEYMRMMG 360
LSSWLHWSAW FLLFFLFLLI AASFMTLLFC VKVKPNVAVL SRSDPSLVLA FLLCFAISTI 420
SFSFMVSTFF SKGMGIQWRD LLSPVNVDDD FCFGQVLGML LLDSVLYGLV TWYMEAVFPG 480
QFGVPQPWYF FIMPSYWCGK PRAVAGKEEE DSDPEKALRN EYFEAEPEDL VAGIKIKHLS 540
KVFRVGNKDR AAVRDLNLNL YEGQITVLLG HNGAGKTTTL SMLTGLFPPT SGRAYISGYE 600
ISQDMVQIRK SLGLCPQHDI LFDNLTVAEH LYFYAQLKGL SRQKCPEEVK QMLHIIGLED 660
KWNSRSRFLS GGMRRKLSIG IALIAGSKVL ILDEPTSGMD AISRRAIWDL LQRQKSDRTI 720
VLTTHFMDEA DLLGDRIAIM AKGELQCCGS SLFLKQKYGA GYHMTLVKEP HCNPEDISQL 780
VHHHVPNATL ESSAGAELSF ILPRESTHRF EGLFAKLEKK QKELGIASFG ASITTMEEVF 840
LRVGKLVDSS MDIQAIQLPA LQYQHERRAS DWAVDSNLCG AMDPSDGIGA LIEEERTAVK 900
LNTGLALHCQ QFWAMFLKKA AYSWREWKMV AAQVLVPLTC VTLALLAINY SSELFDDPML 960
RLTLGEYGRT VVPFSVPGTS QLGQQLSEHL KDALQAEGQE PREVLGDLEE FLIFRASVEG 1020
GGFNERCLVA ASFRDVGERT VVNALFNNQA YHSPATALAV VDNLLFKLLC GPHASIVVSN 1080
FPQPRSALQA AKDQFNEGRK GFDIALNLLF AMAFLASTFS ILAVSERAVQ AKHVQFVSGV 1140
HVASFWLSAL LWDLISFLIP SLLLLVVFKA FDVRAFTRDG HMADTLLLLL LYGWAIIPLM 1200
YLMNFFFLGA ATAYTRLTIF NILSGIATFL MVTIMRIPAV KLEELSKTLD HVFLVLPNHC 1260
LGMAVSSFYE NYETRRYCTS SEVAAHYCKK YNIQYQENFY AWSAPGVGRF VASMAASGCA 1320
YLILLFLIET NLLQRLRGIL CALRRRRTLT ELYTRMPVLP EDQDVADERT RILAPSPDSL 1380
LHTPLIIKEL SKVYEQRVPL LAVDRLSLAV QKGECFGLLG FNGAGKTTTF KMLTGEESLT 1440
SGDAFVGGHR ISSDVGKVRQ RIGYCPQFDA LLDHMTGREM LVMYARLRGI PERHIGACVE 1500
NTLRGLLLEP HANKLVRTYS GGNKRKLSTG IALIGEPAVI FLDEPSTGMD PVARRLLWDT 1560
VARARESGKA IIITSHSMEE CEALCTRLAI MVQGQFKCLG SPQHLKSKFG SGYSLRAKVQ 1620
SEGQQEALEE FKAFVDLTFP GSVLEDEHQG MVHYHLPGRD LSWAKVFGIL EKAKEKYGVD 1680
DYSVSQISLE QVFLSFAHLQ PPTAEEGR 1708
Gene Ontology
GO:0005524
; F:ATP binding; IEA:UniProtKB-KW.
GO:0016887
; F:ATPase activity; IEA:InterPro.
GO:0006200
; P:ATP catabolic process; IEA:GOC.
Interpro
IPR003593
; AAA+_ATPase.
IPR026082
; ABC_A.
IPR003439
; ABC_transporter-like.
IPR017871
; ABC_transporter_CS.
IPR026969
; ABCA3.
IPR027417
; P-loop_NTPase.
Pfam
PF00005
; ABC_tran
SMART
SM00382
; AAA
PROSITE
PS00211
; ABC_TRANSPORTER_1
PS50893
; ABC_TRANSPORTER_2
PRINTS