CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-023331
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Probable nucleolar GTP-binding protein 1 
Protein Synonyms/Alias
  
Gene Name
 CG8801 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
598SRDTLGIKNLAIRKKacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
 Involved in the biogenesis of the 60S ribosomal subunit (By similarity). 
Sequence Annotation
 NP_BIND 175 182 GTP (Potential).
 NP_BIND 221 225 GTP (Potential).
 NP_BIND 289 292 GTP (Potential).  
Keyword
 Complete proteome; GTP-binding; Nucleotide-binding; Nucleus; Reference proteome; Ribosome biogenesis. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 652 AA 
Protein Sequence
MSLYNFKKIM VVPPAKDFID IMLSKTQRKT PTVVHKGYKI SRIRAFYTRK VKYTQQNFHD 60
RLSQIIQDFP KLDDVHPFYA DLMNVLYDKD HYKLALGQLN TARHLVDNVA KDYVRLLKYG 120
DSLYRCKQLK KAALGRMATI MKRQASNLTY LEQVRQHLSR LPTIDPYSRT IIICGFPNVG 180
KSSFINKITR ADVEVQPYAF TTKSLYVGHT DYKYLRWQVI DTPGILDHPL EERNVIEMQA 240
ITALAHLRAC VLYFMDISEQ CGHSLEEQVK LFESIKPLFT NKPLILAINK IDILTPEDLP 300
EERRAIITKL QEDKNIPVML MSTVQETGVM EVKTEACERL LSYRVDQKMR TKKVDNILNR 360
LHVAMPAPRD DKLRAPCIPE KASARLLQNA DKAERKRKLE KEIEEEMGDD YTLDLKKNYS 420
EIPEEERYDI IPEFWQGHNI ADYIDADIFD KLEELEREEG LREESGVYKV PDMTMDETLK 480
EIREIAKQIR GKRFELRDEK RLSSRKNKPV IPRNKQPKVR DRSVQKLVST MEGLGVDMSG 540
SENANFTKSV VDLRRGQVAV GSKKVPMQPL LDKESSAVVR KTGQPLKRAP SRDTLGIKNL 600
AIRKKAQIMA KRDIAKKVTS RGLKGEADRF IGTKMPKHLF SGKRGNGKTD RR 652 
Gene Ontology
 GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW. 
Interpro
 IPR006073; GTP_binding_domain.
 IPR024926; NOG1.
 IPR010674; NOG1_Rossman_fold_dom.
 IPR012973; NOG_C.
 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom. 
Pfam
 PF06858; NOG1
 PF08155; NOGCT 
SMART
  
PROSITE
  
PRINTS
 PR00326; GTP1OBG.