UniProt Accession

 KTHY_YEAST; P00572; D6VWM8 

Genbank Protein ID

 K02116; K01783; Z49557; M15468; L47993; BK006943 

Genbank Nucleotide ID

 AAA35158.1; AAA34486.1; CAA89585.1; AAB05644.1; AAB39283.1; DAA08844.1 

Protein Name

 Thymidylate kinase 

Protein Synonyms/Alias

 dTMP kinase 

Gene Name

 CDC8 

Gene Synonyms/Alias

 YJR057W; J1715 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
27	TQCNILYKKLQPNCK	acetylation	[1]

Reference

 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 

Functional Description

 Catalyzes the conversion of dTMP to dTDP. 

Sequence Annotation

 NP_BIND 12 19 ATP (Probable).  

Keyword

 3D-structure; ATP-binding; Complete proteome; Kinase; Nucleotide biosynthesis; Nucleotide-binding; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 216 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004798; F:thymidylate kinase activity; IDA:SGD.
 GO:0009041; F:uridylate kinase activity; IDA:SGD.
 GO:0006233; P:dTDP biosynthetic process; IDA:SGD.
 GO:0006235; P:dTTP biosynthetic process; IDA:SGD.
 GO:0006227; P:dUDP biosynthetic process; IDA:SGD. 

Interpro

 IPR027417; P-loop_NTPase.
 IPR018095; Thymidylate_kin_CS.
 IPR018094; Thymidylate_kinase. 

Pfam

  

SMART

  

PROSITE

 PS01331; THYMIDYLATE_KINASE 

PRINTS