CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-004927
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ornithine decarboxylase, constitutive 
Protein Synonyms/Alias
  
Gene Name
 speC 
Gene Synonyms/Alias
 b2965; JW5482 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
52SGILALLKRTGFHLPacetylation[1]
169LIHEGSAKDAQKFAAacetylation[1]
173GSAKDAQKFAAKVFHacetylation[1]
183AKVFHADKTYFVLNGacetylation[1]
268IRDVAPEKADLPRPYacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
  
Sequence Annotation
 MOD_RES 347 347 N6-(pyridoxal phosphate)lysine (By  
Keyword
 Complete proteome; Decarboxylase; Lyase; Pyridoxal phosphate; Reference proteome; Spermidine biosynthesis. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 711 AA 
Protein Sequence
MKSMNIAASS ELVSRLSSHR RVVALGDTDF TDVAAVVITA ADSRSGILAL LKRTGFHLPV 60
FLYSEHAVEL PAGVTAVING NEQQWLELES AACQYEENLL PPFYDTLTQY VEMGNSTFAC 120
PGHQHGAFFK KHPAGRHFYD FFGENVFRAD MCNADVKLGD LLIHEGSAKD AQKFAAKVFH 180
ADKTYFVLNG TSAANKVVTN ALLTRGDLVL FDRNNHKSNH HGALIQAGAT PVYLEASRNP 240
FGFIGGIDAH CFNEEYLRQQ IRDVAPEKAD LPRPYRLAII QLGTYDGTVY NARQVIDTVG 300
HLCDYILFDS AWVGYEQFIP MMADSSPLLL ELNENDPGIF VTQSVHKQQA GFSQTSQIHK 360
KDNHIRGQAR FCPHKRLNNA FMLHASTSPF YPLFAALDVN AKIHEGESGR RLWAECVEIG 420
IEARKAILAR CKLFRPFIPP VVDGKLWQDY PTSVLASDRR FFSFEPGAKW HGFEGYAADQ 480
YFVDPCKLLL TTPGIDAETG EYSDFGVPAT ILAHYLRENG IVPEKCDLNS ILFLLTPAES 540
HEKLAQLVAM LAQFEQHIED DSPLVEVLPS VYNKYPVRYR DYTLRQLCQE MHDLYVSFDV 600
KDLQKAMFRQ QSFPSVVMNP QDAHSAYIRG DVELVRIRDA EGRIAAEGAL PYPPGVLCVV 660
PGEVWGGAVQ RYFLALEEGV NLLPGFSPEL QGVYSETDAD GVKRLYGYVL K 711 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0004586; F:ornithine decarboxylase activity; IDA:EcoCyc.
 GO:0030170; F:pyridoxal phosphate binding; IDA:EcoCyc.
 GO:0033387; P:putrescine biosynthetic process from ornithine; IEA:UniProtKB-UniPathway.
 GO:0008295; P:spermidine biosynthetic process; IMP:EcoCyc. 
Interpro
 IPR011006; CheY-like_superfamily.
 IPR005308; OKR_de-COase_N.
 IPR011193; Orn/lys/arg_de-COase.
 IPR000310; Orn/Lys/Arg_deCO2ase_major_dom.
 IPR027464; Ornithine_deCO2ase_N.
 IPR008286; Prn/Lys/Arg_de-COase_C.
 IPR015424; PyrdxlP-dep_Trfase.
 IPR015421; PyrdxlP-dep_Trfase_major_sub1.
 IPR015422; PyrdxlP-dep_Trfase_major_sub2. 
Pfam
 PF01276; OKR_DC_1
 PF03711; OKR_DC_1_C
 PF03709; OKR_DC_1_N 
SMART
  
PROSITE
 PS00703; OKR_DC_1 
PRINTS