UniProt Accession

 NUCKS_MOUSE; Q80XU3; Q8BVD8 

Genbank Protein ID

 AB049825; AK078816; BC039951 

Genbank Nucleotide ID

 BAC06821.1; BAC37408.1; AAH39951.1 

Protein Name

 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 

Protein Synonyms/Alias

 JC7 

Gene Name

 Nucks1 

Gene Synonyms/Alias

 Nucks 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
35	RDSGPPAKKIRSSPR	acetylation	[1]
175	KMPKPRLKATVTPSP	ubiquitination	[2]
184	TVTPSPVKGKAKVGR	ubiquitination	[2]

Reference

 [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

  

Sequence Annotation

 MOD_RES 14 14 Phosphoserine.
 MOD_RES 19 19 Phosphoserine.
 MOD_RES 26 26 Phosphotyrosine (By similarity).
 MOD_RES 54 54 Phosphoserine (By similarity).
 MOD_RES 58 58 Phosphoserine.
 MOD_RES 61 61 Phosphoserine.
 MOD_RES 73 73 Phosphoserine (By similarity).
 MOD_RES 75 75 Phosphoserine.
 MOD_RES 79 79 Phosphoserine.
 MOD_RES 113 113 Phosphoserine.
 MOD_RES 130 130 Phosphoserine.
 MOD_RES 132 132 Phosphoserine.
 MOD_RES 144 144 Phosphoserine (By similarity).
 MOD_RES 179 179 Phosphothreonine.
 MOD_RES 181 181 Phosphoserine.
 MOD_RES 202 202 Phosphothreonine.
 MOD_RES 204 204 Phosphoserine.
 MOD_RES 214 214 Phosphoserine.
 MOD_RES 220 220 Phosphoserine.
 MOD_RES 225 225 Phosphoserine.
 MOD_RES 230 230 Phosphoserine.
 MOD_RES 231 231 Phosphoserine.  

Keyword

 Complete proteome; Nucleus; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 234 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0005634; C:nucleus; IDA:MGI. 

Interpro

 IPR026633; NUCKS1. 

Pfam

  

SMART

  

PROSITE

  

PRINTS