CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039354
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Dipeptidyl peptidase 4 
Protein Synonyms/Alias
  
Gene Name
 Dpp4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
48YTLADYLKNTFRVKSacetylation[1]
137YSIYDLNKRQLITEEacetylation[1]
376FYKIVSDKDGYKHICacetylation[1]
434PGGRNLYKIQLTDHTacetylation[1]
490LHRSTDQKELRVLEDacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 734 AA 
Protein Sequence
MKTPWKVLLG LLGVAALVTI ITVPVVLLNK DEAAADSRRT YTLADYLKNT FRVKSYSLRW 60
VSDSEYLYKQ ENNILLFNAE HGNSSIFLEN STFEIFGDSI SDYSVSPDRL FVLLEYNYVK 120
QWRHSYTASY SIYDLNKRQL ITEEKIPNNT QWITWSQEGH KLAYVWKNDI YVKIEPHLPS 180
HRITSTGKEN VIFNGINDWV YEEEIFGAYS ALWWSPNGTF LAYAQFNDTG VPLIEYSFYS 240
DESLQYPKTV WIPYPKAGAV NPTVKFFIVN TDSLSSTTTT IPMQITAPAS VTTGDHYLCD 300
VAWVSEDRIS LQWLRRIQNY SVMAICDYDK TNLVWNCPTT QEHIETSATG WVGRFRPAEP 360
HFTSDGSSFY KIVSDKDGYK HICQFQKDRK PEQDCTFITK GAWEVISIEA LTSDYLYYIS 420
NEYKEMPGGR NLYKIQLTDH TNKKCLSCDL NPERCQYYSV SLSKEAKYYQ LGCRGPGLPL 480
YTLHRSTDQK ELRVLEDNSA LDKMLQDVQM PSKKLDFIVL NETRFWYQMI LPPHFDKSKK 540
YPLLIDVYAG PCSQKADAAF RLNWATYLAS TENIIVASFD GRGSGYQGDK IMHAINKRLG 600
TLEVEDQIEA ARQFLKMGFV DSKQVAIWGW SYGGYVTSMV LGSGSGVFKC GIAVAPVSRW 660
EYYDSVYTER YMGLPTPEDN LDHYRNSTVM SRAENFKQVE YLLIHGTADD NVHFQQSAQI 720
SKALVDAGVD FQAM 734 
Gene Ontology
 GO:0016324; C:apical plasma membrane; IEA:Compara.
 GO:0009986; C:cell surface; IEA:Compara.
 GO:0030139; C:endocytic vesicle; IEA:Compara.
 GO:0070062; C:extracellular vesicular exosome; IEA:Compara.
 GO:0046581; C:intercellular canaliculus; IEA:Compara.
 GO:0071438; C:invadopodium membrane; IEA:Compara.
 GO:0030027; C:lamellipodium; IEA:Compara.
 GO:0008239; F:dipeptidyl-peptidase activity; IEA:Compara.
 GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
 GO:0043542; P:endothelial cell migration; IEA:Compara.
 GO:0010716; P:negative regulation of extracellular matrix disassembly; IEA:Compara.
 GO:0008284; P:positive regulation of cell proliferation; IEA:Compara.
 GO:0006508; P:proteolysis; IEA:InterPro.
 GO:0033632; P:regulation of cell-cell adhesion mediated by integrin; IEA:Compara.
 GO:0001666; P:response to hypoxia; IEA:Compara.
 GO:0042110; P:T cell activation; IEA:Compara.
 GO:0031295; P:T cell costimulation; IEA:Compara. 
Interpro
 IPR002471; Pept_S9_AS.
 IPR001375; Peptidase_S9.
 IPR002469; Peptidase_S9B. 
Pfam
 PF00930; DPPIV_N
 PF00326; Peptidase_S9 
SMART
  
PROSITE
 PS00708; PRO_ENDOPEP_SER 
PRINTS