CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003366
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Uncharacterized HTH-type transcriptional regulator YegW 
Protein Synonyms/Alias
  
Gene Name
 yegW 
Gene Synonyms/Alias
 b2101; JW2088 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
110QQVVLRGKKPDTLWVacetylation[1]
144GSDVFLLKRIRYVDEacetylation[1]
219KIPVLVIKQVALDQQacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
  
Sequence Annotation
 DOMAIN 22 90 HTH gntR-type.
 DNA_BIND 50 69 H-T-H motif (Potential).  
Keyword
 Complete proteome; DNA-binding; Reference proteome; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 248 AA 
Protein Sequence
MEQAHTQLIA QLNERILAAD NTPLYIKFAE TVKNAVRSGV LEHGNILPGE RDLSQLTGVS 60
RITVRKAMQA LEEEGVVTRS RGYGTQINNI FEYSLKEARG FSQQVVLRGK KPDTLWVNKR 120
VVKCPEEVAQ QLAVEAGSDV FLLKRIRYVD EEAVSIEESW VPAHLIHDVD AIGISLYDYF 180
RSQHIYPQRT RSRVSARMPD AEFQSHIQLD SKIPVLVIKQ VALDQQQRPI EYSISHCRSD 240
LYVFVCEE 248 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR000524; Tscrpt_reg_HTH_GntR.
 IPR011663; UTRA.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF00392; GntR
 PF07702; UTRA 
SMART
 SM00345; HTH_GNTR
 SM00866; UTRA 
PROSITE
 PS50949; HTH_GNTR 
PRINTS
 PR00035; HTHGNTR.