CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-014801
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Uncharacterized family 31 glucosidase KIAA1161 
Protein Synonyms/Alias
  
Gene Name
 Kiaa1161 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
672APVLEPGKQERDVYLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Putative glucosidase (By similarity). 
Sequence Annotation
 ACT_SITE 462 462 By similarity.
 ACT_SITE 465 465 By similarity.
 ACT_SITE 527 527 Proton donor (By similarity).
 CARBOHYD 239 239 N-linked (GlcNAc...).
 CARBOHYD 249 249 N-linked (GlcNAc...).
 CARBOHYD 455 455 N-linked (GlcNAc...) (Potential).  
Keyword
 Complete proteome; Glycoprotein; Glycosidase; Hydrolase; Membrane; Reference proteome; Signal-anchor; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 716 AA 
Protein Sequence
MSQNLQETSQ AYPRHRPGSH AGPKSLKVTP RATMYTFLPD NFSPAKPKPT KELRPLLCSA 60
VLGLLLVLAA VVAWCYYSAS LRKAERLRAE LLDLNRGGFS IRNQKGEQVF RLAFRSGALD 120
LDSCSRDGAL LGCSRAADGR PLHFFIQTVR PKDTVMCYRV RWEEAVPGRA VEHAMFLGDA 180
AAHWYGGAEM RTQHWPIRLD GQQEPQPFVT SDVYSSDAAF GGILERYWLS SRAAAIKVND 240
SVPFHLGWNS TERSMRLQAR YHDTSYKPPA GRTAAPELSY RVCVGSDVTS IHKYMVRRYF 300
NKPSRVPASE AFRDPIWSTW ALHGRAVDQN KVLQFAQQIR QHRFNSSHLE IDDMYTPAYG 360
DFNFDEGKFP NASDMFRRLR DAGFRVTLWV HPFVNYNSSS FGEGVERELF VREPTGRLPA 420
LVRWWNGIGA VLDFTHPEAR EWFQGHLRRL RLRYNVTSFK FDAGEVSYLP RDFSTYRPLS 480
DPSVWSRRYT EMAEPFFSLA EVRVGYQSQN ISCFFRLVDR DSVWGYDLGL RSLIPAVLTV 540
SMLGYPFILP DMIGGNAVPE RTAGRQDGPG PERELYVRWL EVAAFMPAMQ FSIPPWQYDA 600
EVVAIAHKFA ALRASLVAPL LLELAGEITD TGDPIVRPLW WIAPGDETAH RIDSQFLIGD 660
TLLVAPVLEP GKQERDVYLP AGKWRSYKGE LFDKTPVLLT DYPVDLDEVA YFTWAS 716 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0031965; C:nuclear membrane; IDA:MGI.
 GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
 GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
 GO:0043568; P:positive regulation of insulin-like growth factor receptor signaling pathway; IMP:MGI.
 GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:MGI.
 GO:0048741; P:skeletal muscle fiber development; IMP:MGI. 
Interpro
 IPR013785; Aldolase_TIM.
 IPR000322; Glyco_hydro_31.
 IPR017853; Glycoside_hydrolase_SF. 
Pfam
 PF01055; Glyco_hydro_31 
SMART
  
PROSITE
 PS00129; GLYCOSYL_HYDROL_F31_1
 PS00707; GLYCOSYL_HYDROL_F31_2 
PRINTS