UniProt Accession

 A1AG1_HUMAN; P02763; B7ZKQ5; Q5T539; Q5U067; Q8TC16 

Genbank Protein ID

 X02544; M13692; X05779; X05780; X05781; X05782; X05783; X05784; X06676; X06680; BT019790; AK312035; AL356796; CH471090; BC104818; BC104820; BC143313; BC143314; BC026238 

Genbank Nucleotide ID

 CAA26397.1; AAA35515.1; CAA29229.1; CAA29229.1; CAA29229.1; CAA29229.1; CAA29229.1; CAA29229.1; AAV38593.1; BAG34972.1; CAI16859.1; EAW87416.1; AAI04819.1; AAI04821.1; AAI43314.1; AAI43315.1; AAH26238.1 

Protein Name

 Alpha-1-acid glycoprotein 1 

Protein Synonyms/Alias

 AGP 1; Orosomucoid-1; OMD 1 

Gene Name

 ORM1 

Gene Synonyms/Alias

 AGP1 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
170	LDCLRIPKSDVVYTD	glycation	[1]

Reference

 [1] Proteomic profiling of nonenzymatically glycated proteins in human plasma and erythrocyte membranes.
 Zhang Q, Tang N, Schepmoes AA, Phillips LS, Smith RD, Metz TO.
 J Proteome Res. 2008 May;7(5):2025-32. [PMID: 18396901] 

Functional Description

 Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability in the body. Appears to function in modulating the activity of the immune system during the acute-phase reaction. 

Sequence Annotation

 MOD_RES 19 19 Pyrrolidone carboxylic acid.
 CARBOHYD 33 33 N-linked (GlcNAc...) (complex).
 CARBOHYD 56 56 N-linked (GlcNAc...).
 CARBOHYD 72 72 N-linked (GlcNAc...) (complex).
 CARBOHYD 93 93 N-linked (GlcNAc...).
 CARBOHYD 103 103 N-linked (GlcNAc...).
 DISULFID 23 165
 DISULFID 90 183  

Keyword

 3D-structure; Acute phase; Complete proteome; Direct protein sequencing; Disulfide bond; Glycoprotein; Polymorphism; Pyrrolidone carboxylic acid; Reference proteome; Secreted; Signal; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 201 AA 

Protein Sequence

Gene Ontology

 GO:0005615; C:extracellular space; TAS:ProtInc.
 GO:0006953; P:acute-phase response; TAS:ProtInc.
 GO:0002682; P:regulation of immune system process; IEA:InterPro.
 GO:0006810; P:transport; IEA:UniProtKB-KW. 

Interpro

 IPR001500; A1A_glycop.
 IPR012674; Calycin.
 IPR011038; Calycin-like.
 IPR000566; Lipocln_cytosolic_FA-bd_dom. 

Pfam

 PF00061; Lipocalin 

SMART

  

PROSITE

 PS00213; LIPOCALIN 

PRINTS

 PR00708; A1AGLPROTEIN.