| Tag | Content |
|---|
| CPLM ID | CPLM-011493 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Ribosome biogenesis protein TSR1 |
Protein Synonyms/Alias | 20S rRNA accumulation protein 1 |
Gene Name | TSR1 |
Gene Synonyms/Alias | YDL060W |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 641 | NSPNNVHKYERFLHP | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | Required for 40S ribosomal subunit synthesis. Required for normal export of the pre-40S particles from the nucleus to the cytoplasm. Its subcellular location and association with pre-40S subunitshifts from mixed cytoplasm/nucleus to all nuclear in RPS19 disruptions, suggesting it acts after the ribosomal protein. |
Sequence Annotation | |
Keyword | Complete proteome; Cytoplasm; Nucleus; Reference proteome; Ribosome biogenesis. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 788 AA |
Protein Sequence | MAGHSHRSSL KNGHKSYKSK HASKGALKRL YKGKVEKEPV GTGKPDKQVS KLQRKNKAKQ 60
LRAQRILDSI ENRKLFEGKN GAAKIITIVP LVNDLDPLDI LYKLLKCADD EGIMVQEVDS 120
KRIFNVHIKK FKSNLKIIIP DMTNFLNILD CAKVADFVVF GLSGVQEVDE EFGEQIIRAL 180
ELQGIASYIG VISNLSAVHE KEKFQLDVKQ SLESYFKHFF PSEERVYNLE KNSDALNVLR 240
TLCQRLPRSI NWRDNRGYVV ADFVDFVETS PDSGDLVIEG TVRGIGFNAN RLVHIPDFGD 300
FQLNKIEKIS ESSQKRKIIK EKATDSLSLE LDLQTVFESN MNRDTLDEYA PEGTEDWSDY 360
DEDFEYDGLT TARYDDHGFL PGREQTSKKA AVPKGTSDYQ AKWYLDDVID ANEEEEAEQT 420
NGKDETMMEI DDEMMVEQDN EEVAGDEEYD IEDNEGFEEL SPEEEERQLR EFRDMEKEDR 480
EFPDEIELEP SESAIERLKR YRGLKNLYNC DWQVDEKDPS SPAEWKRLLR IGNYKNTKNR 540
IIKETKNEAQ AIAGDRIRMF IRFPKFLLEK IQDPKQLLFA VYGLLLHEHK NAVVNFSLQR 600
WEQYDKPVPS QEPIVVQYGV RRYTIQPLFS QGSNSPNNVH KYERFLHPDT VSVATCIAPV 660
DFTQSPAIFF KPSPTDAKNI ELIGHGTFLN ADHSRILAKR AILTGHPFRF HKTVVTVRYM 720
FFRPEDVEWF KSIPLFTKSG RSGFIKESLG THGYFKATFD GKLSAQDVVA MSLYKRMWPM 780
PSLPWNGM 788 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |