CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013424
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 C2 domain-containing protein 3 
Protein Synonyms/Alias
  
Gene Name
 C2cd3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
581FSKSGLGKTALITGVacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
 DOMAIN 1168 1306 C2 1.
 DOMAIN 1603 1709 C2 2.  
Keyword
 Alternative splicing; Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2323 AA 
Protein Sequence
MKQRKGQGPG GGRGRKKRGL SDISPSTSLP PLVEGQLRCF LKLTINKVVW KIAKPPTSVL 60
VRVRWWGETS DGTLFCPRDA LQTEPKAVRT TTRYGIRCGP KQFTSYLTDM AVLVLEVITK 120
FDHLPVGRVQ ISGLAQLSPT HQINGFFTIV SPASKKLGEL QVSLALEPLS ETYDSYKPLP 180
ATEVTKNVLL SERELRENTE SSNTQSMIPS RSCRGPAIKI DGKELAGHSS RSTTPRGKDH 240
LYFAENSDAV KGSLCGLQQH LNQGTNVETI TLRGKAPQKQ LSLLNSSEFQ PQISTVAKSH 300
SDSCILSSNT PPAKDLLSAL LEQGNKLRNA MLISAMNSNP DTSMLLDKVP PPMTEAIPRS 360
SALNSSENHF KGHSADHLLP LADTGAIQLL LGSAELSQGH FWNGLGSPPD SPTPGSDEYC 420
SSDLNDPQYD QSLLENLFYT VPKSDVGTSE LPSEDDGVEP SRTMNQSKAS GRSKVVESKE 480
QKQKRAAVKK SRNPIDQQEL SRTPGHTPAM SLSVDRLALL GRVHSVRIIV ETMGVPPDSP 540
HMTPSRKNFA GKPPKPTAAK KRTFFVEYHF PVGFSKSGLG KTALITGVVR LASSKITDGV 600
VKFQQRFVCP VEFGGPMIEH WWDSNLIFQI YAKKTPQKKP EVIGSASLPL RAVIQSELLS 660
FSSQLPVQQE NGLSSLGPLK VTMELVLGHK DFTGISAKLS SSTQPAPVSA ATSSDTILPE 720
TGQDTACTRN PQSSNKIHEE TTKKTQNLVL PDQESANSVA SNSSIFMAVP SCNLVHQING 780
SNKESGLLLH VLLMVPDGKD FVFGEREKQP SCNVYLNCKL FSTEEVTRSV VSWGTAQPVF 840
NFSQVIPVSL TSKCLERLKN NVMIIETWNK VRSPGQDKLL GLVKLPLHQF YMSFKDPKIS 900
RLLLDARYPV VAVDSYMPVI DVFSGHQNGS LRVFLAMGSS AQIMMLQRLK NEEGTLPPFS 960
PRPAHFLDQP PVASVAMPEK QGTRLMEHHF EFCVAMVKGL MPLQATVWGE ADCYVQYYFP 1020
FQDSQPSVLQ GPDFLENGIT LKPFRTSTTL CVPDPVFNSE HHHSLLLPTD VPVQRLLLSA 1080
FSSQGLVPGG GVQFEVWCRY YYPNVRDQMV AKGTLPLSRV CAMVTMQYRE DVGMQSFNLP 1140
LTSRLEHSKE LKNQSSGFLD VGLRYRRSPR TAEGILAARA VSISVHIIRA CGLQAAAKAL 1200
AEQEPALQFS ATVGVNASVT AHLSFLPKGE QRQTRPVACS FCPEFSHHIE FPCNLVTQHC 1260
SGEACFLAEL LEFAEIIFAI YHENTKSVSD ITSIQSCKDY LLGIVKVPTK DLLVKRSGIT 1320
GWYPVILPED KGLPQDLDLM QKIVGGLELS VSFAHPGDRE RVLEAAELLG WSFESIPKDL 1380
VKKEEEVPAT VTISTPRLWL PIHCVLLAGH MNIHKNTYCY LRYKLYNQEA FWTPLRKPKE 1440
STNKNQVLIT FKASKRAEVT RSQSLLWYFR EEKLEIQVWR AYGNDNLERP HQTDSWIGSA 1500
YVDLSRLGEK SPRTLTISGV YPLFGRNASD LSGAALRIHV LLSPLSPHTE PARELDSMDC 1560
SSHSESEQHP RKSDALQLSP PHVLQTSPTS TQVHGNSAAA QVCPAQEGPP ELAGTFAVSI 1620
LVERAMHLSL KGSPLTDRKV SVPSCCVSFA TATELSPVYT HVVENTDSPI WGFHQQARLS 1680
KELLLDPHQT LVFKVWHKGD EERVVGFASV DLSPLLSGFQ FICGWYNITD FSGECQGQIK 1740
VAISPMESLM HLKEERQARR GIDTPGALIP LFSALSFPAS AGCDAFPRPI ARHVEGQLAH 1800
TSPKEDGLSS PARNGAIRSQ AARHEEHVQN IRRFHESLQH GEAVLTSDEK LTTAPSSSHT 1860
SILTSLRKNL SELDEIQKYF SQKLSKPFLP FSSQSSPAVS QSQESQRDPV AAGTGRQDPE 1920
NQCILEKSNH LVSQVSSLIS DLQTLTRGSQ AALTSQQARS RSRAVTTIPD AQGTEAAGEG 1980
STTLEEPLAG AIEASTDSLP PPVEEPSKGG GMLHESLEQT MPITRVQSID DTEVGPDYSD 2040
EDYEEDIIEP RTLNEITTVT DRTSPWSSFM SDMSEVLSPQ PTEVQREGPS CPPEPFPREE 2100
LKVKSSPQKA VSPQPAQGSP SQSGVCEGGA YKIEVEDLAS AKPQPVPSLT FSEAQEGSDS 2160
VGWRASQINQ VRKPMPEMLA ESEAFSSEFS DSSESFETFP LHLPSQSKRE DYKDSPAVRQ 2220
KQVPTGSEVS TRQTLLLPEP VVVPNFFLPP QQLEASLRMI SHSPGLPPAA TTDQDKSEAT 2280
RGALAQRPCR PRPYSIPPNL PEEETRRIAR IFSSQYSKKT EET 2323 
Gene Ontology
 GO:0005932; C:microtubule basal body; IDA:MGI.
 GO:0007420; P:brain development; IMP:MGI.
 GO:0042384; P:cilium assembly; IMP:MGI.
 GO:0042733; P:embryonic digit morphogenesis; IMP:MGI.
 GO:0001947; P:heart looping; IMP:MGI.
 GO:0001701; P:in utero embryonic development; IMP:MGI.
 GO:0021997; P:neural plate axis specification; IMP:MGI.
 GO:0021915; P:neural tube development; IMP:MGI.
 GO:0016485; P:protein processing; IMP:MGI.
 GO:0030162; P:regulation of proteolysis; IDA:MGI.
 GO:0008589; P:regulation of smoothened signaling pathway; IMP:MGI. 
Interpro
 IPR000008; C2_Ca-dep.
 IPR008973; C2_Ca/lipid-bd_dom_CaLB. 
Pfam
 PF00168; C2 
SMART
 SM00239; C2 
PROSITE
 PS50004; C2 
PRINTS