CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003688
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Polyadenylate-binding protein 4-like 
Protein Synonyms/Alias
 PABP-4-like; Poly(A)-binding protein 4-like 
Gene Name
 PABPC4L 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
107VFIKNLDKSIDNKTLacetylation[1]
107VFIKNLDKSIDNKTLubiquitination[2]
Reference
 [1] Lysine acetylation targets protein complexes and co-regulates major cellular functions.
 Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M.
 Science. 2009 Aug 14;325(5942):834-40. [PMID: 19608861]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
 May bind RNA (Potential). 
Sequence Annotation
 DOMAIN 10 88 RRM 1.
 DOMAIN 98 174 RRM 2.
 DOMAIN 190 267 RRM 3.
 DOMAIN 293 369 RRM 4.  
Keyword
 Complete proteome; Polymorphism; Reference proteome; Repeat; RNA-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 370 AA 
Protein Sequence
MNVAAKYRMA SLYVGDLHAD VTEDLLFRKF STVGPVLSIR ICRDQVTRRS LGYAYVNFLQ 60
LADAQKALDT MNFDIIKGKS IRLMWSQRDA YLRRSGIGNV FIKNLDKSID NKTLYEHFSA 120
FGKILSSKVM SDDQGSKGYA FVHFQNQSAA DRAIEEMNGK LLKGCKVFVG RFKNRKDREA 180
ELRSKASEFT NVYIKNFGGD MDDERLKDVF SKYGKTLSVK VMTDSSGKSK GFGFVSFDSH 240
EAAKKAVEEM NGRDINGQLI FVGRAQKKVE RQAELKQMFE QLKRERIRGC QGVKLYIKNL 300
DDTIDDEKLR NEFSSFGSIS RVKVMQEEGQ SKGFGLICFS SPEDATKAMT EMNGRILGSK 360
PLSIALAQRH 370 
Gene Ontology
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0003723; F:RNA binding; IEA:UniProtKB-KW. 
Interpro
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR006515; PABP_1234.
 IPR000504; RRM_dom. 
Pfam
 PF00076; RRM_1 
SMART
 SM00360; RRM 
PROSITE
 PS50102; RRM 
PRINTS