UniProt Accession

 H31_CANAL; Q59VN2 

Genbank Protein ID

 AACQ01000120; AACQ01000121; AACQ01000215; AACQ01000218 

Genbank Nucleotide ID

 EAK94607.1; EAK94561.1; EAK91843.1; EAK91799.1 

Protein Name

 Histone H3.1/H3.2 

Protein Synonyms/Alias

  

Gene Name

 HHT1; HHT2 

Gene Synonyms/Alias

 CaO19.1061; CaO19.8663; CaO19.1853; CaO19.9411 

Created Date

 July 27, 2013 

Organism

 Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) 

NCBI Taxa ID

 237561 

Lysine Modification

Position	Peptide	Type	References
57	REIRRFQKSTELLIR	acetylation	[1]

Reference

 [1] Histone acetyltransferase Rtt109 is required for Candida albicans pathogenesis.
 Lopes da Rosa J, Boyartchuk VL, Zhu LJ, Kaufman PD.
 Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1594-9. [PMID: 20080646] 

Functional Description

 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). 

Sequence Annotation

 MOD_RES 5 5 N6,N6,N6-trimethyllysine; alternate (By
 MOD_RES 5 5 N6,N6-dimethyllysine; alternate (By
 MOD_RES 5 5 N6-methyllysine; alternate (By
 MOD_RES 10 10 N6-acetyllysine; alternate (By
 MOD_RES 10 10 N6-methyllysine; alternate (By
 MOD_RES 11 11 Phosphoserine (By similarity).
 MOD_RES 15 15 N6,N6-dimethyllysine; alternate (By
 MOD_RES 15 15 N6-acetyllysine; alternate (By
 MOD_RES 19 19 N6-acetyllysine; alternate (By
 MOD_RES 19 19 N6-methyllysine; alternate (By
 MOD_RES 24 24 N6-acetyllysine; alternate (By
 MOD_RES 24 24 N6-methyllysine; alternate (By
 MOD_RES 28 28 N6,N6,N6-trimethyllysine; alternate (By
 MOD_RES 28 28 N6,N6-dimethyllysine; alternate (By
 MOD_RES 28 28 N6-acetyllysine; alternate (By
 MOD_RES 28 28 N6-methyllysine; alternate (By
 MOD_RES 37 37 N6,N6,N6-trimethyllysine; alternate (By
 MOD_RES 37 37 N6,N6-dimethyllysine; alternate (By
 MOD_RES 37 37 N6-acetyllysine; alternate (By
 MOD_RES 37 37 N6-methyllysine; alternate (By
 MOD_RES 57 57 N6-acetyllysine (By similarity).
 MOD_RES 65 65 N6-acetyllysine (By similarity).
 MOD_RES 80 80 N6,N6,N6-trimethyllysine; alternate (By
 MOD_RES 80 80 N6,N6-dimethyllysine; alternate (By
 MOD_RES 80 80 N6-methyllysine; alternate (By  

Keyword

 Acetylation; Chromosome; Complete proteome; DNA damage; DNA repair; DNA-binding; Methylation; Nucleosome core; Nucleus; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 136 AA 

Protein Sequence

Gene Ontology

 GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
 GO:0006334; P:nucleosome assembly; IEA:InterPro. 

Interpro

 IPR009072; Histone-fold.
 IPR007125; Histone_core_D.
 IPR000164; Histone_H3. 

Pfam

 PF00125; Histone 

SMART

 SM00428; H3 

PROSITE

 PS00322; HISTONE_H3_1
 PS00959; HISTONE_H3_2 

PRINTS

 PR00622; HISTONEH3.