CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037781
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 
Protein Synonyms/Alias
  
Gene Name
 SIRT3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
122GGSSDKGKLSLQDVAacetylation[1]
Reference
 [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 345 AA 
Protein Sequence
MAFWGWRAAA ALRLWGRVVE RVEAGGGVGP FQACGCRLVL GGRDDVSAGL RGSHGARGEP 60
LDPARPLQRP PRPEVPRAFR RQPRAAAPSF FFSSIKGGRR SISFSVGASS VVGSGGSSDK 120
GKLSLQDVAE LIRARACQRV VVMVGAGIST PSGIPDFRSP GSGLYSNLQQ YDLPYPEAIF 180
ELPFFFHNPK PFFTLAKELY PGNYKPNVTH YFLRLLHDKG LLLRLYTQNI DGLERVSGIP 240
ASKLVEAHGT FASATCTVCQ RPFPGEDIRV EPFASLTEAV RSSVPRLLIN RDLVGPLAWH 300
PRSRDVAQLG DVVHGVESLV ELLGWTEEMR DLVQRETGKL DGPDK 345 
Gene Ontology
 GO:0070403; F:NAD+ binding; IEA:InterPro. 
Interpro
 IPR003000; Sirtuin.
 IPR026590; Ssirtuin_cat_dom. 
Pfam
 PF02146; SIR2 
SMART
  
PROSITE
 PS50305; SIRTUIN 
PRINTS