| Tag | Content |
|---|
| CPLM ID | CPLM-001116 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Pentatricopeptide repeat-containing protein 1, mitochondrial |
Protein Synonyms/Alias | |
Gene Name | PTCD1 |
Gene Synonyms/Alias | KIAA0632 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 241 | LRQQLQAKNFELNLK | ubiquitination | [1] | | 659 | DGFRAYYKQWLTVMP | ubiquitination | [1] | | 676 | ETPHPWQKFRTKPQG | ubiquitination | [1] |
|
Reference | [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C. Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [ PMID: 21890473] |
Functional Description | Mitochondrial protein implicated in negative regulation of leucine tRNA levels, as well as negative regulation of mitochondria-encoded proteins and COX activity. Affects also the 3' processing of mitochondrial tRNAs. |
Sequence Annotation | REPEAT 135 171 PPR 1.
REPEAT 172 206 PPR 2.
REPEAT 207 245 PPR 3.
REPEAT 246 280 PPR 4.
REPEAT 281 317 PPR 5.
REPEAT 318 354 PPR 6.
REPEAT 519 553 PPR 7.
REPEAT 554 585 PPR 8.
REPEAT 586 620 PPR 9. |
Keyword | Complete proteome; Mitochondrion; Polymorphism; Reference proteome; Repeat; tRNA processing. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 700 AA |
Protein Sequence | MDFVRLARLF ARARPMGLFI LQHLDPCRAR WAGGREGLMR PMWAPFSSSS SQLPLGQERQ 60
ENTGSLGSDP SHSNSTATQE EDEEEEESFG TLSDKYSSRR LFRKSAAQFH NLRFGERRDE 120
QMEPEPKLWR GRRNTPYWYF LQCKHLIKEG KLVEALDLFE RQMLKEERLQ PMESNYTVLI 180
GGCGRVGYLK KAFNLYNQMK KRDLEPSDAT YTALFNVCAE SPWKDSALQS ALKLRQQLQA 240
KNFELNLKTY HALLKMAAKC ADLRMCLDVF KEIIHKGHVV TEETFSFLLM GCIQDKKTGF 300
RYALQVWRLM LSLGLQPSRD SYNLLLVAAR DCGLGDPQVA SELLLKPREE ATVLQPPVSR 360
QRPRRTAQAK AGNLMSAMLH VEALERQLFL EPSQALGPPE PPEARVPGKA QPEVDTKAEP 420
SHTAALTAVA LKPPPVELEV NLLTPGAVPP TVVSFGTVTT PADRLALIGG LEGFLSKMAE 480
HRQQPDIRTL TLLAEVVESG SPAESLLLAL LDEHQVEADL TFFNTLVRKK SKLGDLEGAK 540
ALLPVLAKRG LVPNLQTFCN LAIGCHRPKD GLQLLTDMKK SQVTPNTHIY SALINAAIRK 600
LNYTYLISIL KDMKQNRVPV NEVVIRQLEF AAQYPPTFDR YQGKNTYLEK IDGFRAYYKQ 660
WLTVMPAEET PHPWQKFRTK PQGDQDTGKE ADDGCALGGR 700 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |