| Tag | Content |
|---|
| CPLM ID | CPLM-001188 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc finger protein 254 |
Protein Synonyms/Alias | Bone marrow zinc finger 5; BMZF-5; Hematopoietic cell-derived zinc finger protein 1; HD-ZNF1; Zinc finger protein 539; Zinc finger protein 91-like |
Gene Name | ZNF254 |
Gene Synonyms/Alias | BMZF5; ZNF539; ZNF91L |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 385 | YKCLECGKAFKQLST | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May be involved in transcriptional regulation. |
Sequence Annotation | DOMAIN 13 84 KRAB.
ZN_FING 210 232 C2H2-type 1; degenerate.
ZN_FING 238 260 C2H2-type 2; degenerate.
ZN_FING 266 288 C2H2-type 3.
ZN_FING 294 316 C2H2-type 4.
ZN_FING 322 344 C2H2-type 5.
ZN_FING 350 372 C2H2-type 6.
ZN_FING 378 400 C2H2-type 7.
ZN_FING 406 428 C2H2-type 8.
ZN_FING 434 456 C2H2-type 9.
ZN_FING 462 484 C2H2-type 10.
ZN_FING 490 512 C2H2-type 11.
ZN_FING 518 540 C2H2-type 12.
ZN_FING 546 568 C2H2-type 13.
ZN_FING 574 596 C2H2-type 14.
ZN_FING 602 624 C2H2-type 15. |
Keyword | Alternative splicing; Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 659 AA |
Protein Sequence | MPGPPRSLEM GLLTFRDVAI EFSLEEWQHL DIAQQNLYRN VMLENYRNLA FLGIAVSKPD 60
LITCLEQGKE PWNMKRHEMV DEPPGMCPHF AQDLWPEQGM EDSFQKAILR RYGKYGHENL 120
QLRKGCKSVD EYKVNKEGYN GLNQCFTTAQ SKVFQCDKYL KVFYKFLNSN RPKIRHTEKK 180
SFKCKKRVKL FCMLSHKTQH KSIYHREKSY KCKECGKTFN WSSTLTNHRK IYTEEKPYKC 240
EEYNKSPKQL STLTTHEIIH AGEKLYKCEE CGEAFNRSSN LTTHKIIHTG EKPYKCEECG 300
KAFIWSSTLT EHKKIHTRKK PYKCEECGKA FIWSSTLTRH KRMHTGEKPY KCEECGKAFS 360
QSSTLTTHKI IHTGEKRYKC LECGKAFKQL STLTTHKIIH VGEKLYKCEE CGKGFNRSSN 420
LTTHKIIHTG EKPYKCEECG KAFIWSSTLT KHKRIHTREK PYKCEECGKA FIWSSTLTRH 480
KRMHTGEKPY KCEECGKSFS QSSTLTTHKI IHTGEKPYKC EECGKAFNWS STLTKHKIIH 540
TEEKPYKCEK CGKAFKQSSI LTNHKRIHTG EKPYKCEECG KSFNRSSTFT KHKVIHTGVK 600
PYKCEECGKA FFWSSTLTKH KRIHTGEQPY KWEKFGKAFN RSSHLTTDKI THWREILQV 659 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |