UniProt Accession

 IF1A_YEAST; P38912; D6W086 

Genbank Protein ID

 U11585; Z49260; AY557964; BK006946 

Genbank Nucleotide ID

 AAA82039.1; CAA89243.1; AAS56290.1; DAA10160.1 

Protein Name

 Eukaryotic translation initiation factor 1A 

Protein Synonyms/Alias

 eIF-1A; Eukaryotic translation initiation factor 4C; eIF-4C 

Gene Name

 TIF11 

Gene Synonyms/Alias

 YMR260C; YM8156.02C 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
94	DQCDVVHKYNLDEAR	ubiquitination	[1]

Reference

 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 

Functional Description

 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. 

Sequence Annotation

 DOMAIN 22 96 S1-like.  

Keyword

 Complete proteome; Initiation factor; Protein biosynthesis; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 153 AA 

Protein Sequence

Gene Ontology

 GO:0005840; C:ribosome; TAS:SGD.
 GO:0003725; F:double-stranded RNA binding; IDA:SGD.
 GO:0003743; F:translation initiation factor activity; TAS:SGD. 

Interpro

 IPR012340; NA-bd_OB-fold.
 IPR006196; RNA-binding_domain_S1_IF1.
 IPR001253; TIF_eIF-1A.
 IPR018104; TIF_eIF-1A_CS. 

Pfam

 PF01176; eIF-1a 

SMART

 SM00652; eIF1a 

PROSITE

 PS01262; IF1A
 PS50832; S1_IF1_TYPE 

PRINTS