CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027430
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Heat shock protein 101, putative 
Protein Synonyms/Alias
  
Gene Name
 PF11_0175 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Plasmodium falciparum (isolate 3D7) 
NCBI Taxa ID
 36329 
Lysine Modification
Position
Peptide
Type
References
329TDAANLLKPVLSKGEacetylation[1]
Reference
 [1] Extensive lysine acetylation occurs in evolutionarily conserved metabolic pathways and parasite-specific functions during Plasmodium falciparum intraerythrocytic development.
 Miao J, Lawrence M, Jeffers V, Zhao F, Parker D, Ge Y, Sullivan WJ Jr, Cui L.
 Mol Microbiol. 2013 Aug;89(4):660-75. [PMID: 23796209
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Chaperone; Complete proteome; Nucleotide-binding; Reference proteome; Stress response. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 906 AA 
Protein Sequence
MTRRYLKYYI FVTLLFFVQV INNVLCAPDN KQEQGKYLNR TINILNAGKN IAKSYGHNKL 60
KPIHILSALA KSDYGSTLFK ENNVNAANLK EYIDIALEQT RAGAPLDNKS KIVNSAEVKE 120
TLALAEAAAN KYKSPKVDVE HLLSGLSNDE LVNEIFNEVY LTDEAIKAIL KRKFEKTKKD 180
KDGKTGTLYI EQFGSNMNEK VRNGKLQGIY GRDEEIRAII ESLLRYNKNS PVLVGNPGTG 240
KTTIVEGLVY RIEKGDVPKE LQGYTVISLN FRKFTSGTSY RGEFETRMKN IIKELKNKKN 300
KIILFVDEIH LLLGAGKAEG GTDAANLLKP VLSKGEIKLI GATTIAEYRK FIESCSAFER 360
RFEKILVEPP SVDMTVKILR SLKSKYENFY GINITDKALV AAAKISDRFI KDRYLPDKAI 420
DLLNKACSFL QVQLSGKPRI IDVTERDIER LSYEISTLEK DVDKVSKKKY NKLIKEFEEK 480
KEQLKKYYEE YVITGERLKR KKEIEKKLND LKELTQNYVY SNKEPPIELQ NSLKEAQQKY 540
LELYKETVAY VEAKTHNAMN VDAVYQEHVS YIYLRDSGMP LGSLSFESSK GALKLYNSLS 600
KSIIGNEDII KSLSDAVVKA ATGMKDPEKP IGTFLFLGPT GVGKTELAKT LAIELFNSKD 660
NLIRVNMSEF TEAHSVSKIT GSPPGYVGFS DSGQLTEAVR EKPHSVVLFD ELEKAHADVF 720
KVLLQILGDG YINDNHRRNI DFSNTIIIMT SNLGAELFKK KLFFDADNSG TPEYKRVMED 780
VRLSLIKKCK KVFKPEFVNR IDKIGVFEPL NKKNLHKIVA LRFKKLEKRL EEKNIQVSVS 840
EKAIDYIIDQ SYDPELGARP TLIFIESVIM TKFAIMYLKK ELVDDMDVFV DYNSKAKNLV 900
INLSKT 906 
Gene Ontology
 GO:0020011; C:apicoplast; ISS:GeneDB_Pfalciparum.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
 GO:0019538; P:protein metabolic process; IEA:InterPro.
 GO:0009408; P:response to heat; ISS:GeneDB_Pfalciparum.
 GO:0006986; P:response to unfolded protein; ISS:GeneDB_Pfalciparum. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR013093; ATPase_AAA-2.
 IPR003959; ATPase_AAA_core.
 IPR018368; Chaperonin_ClpA/B_CS.
 IPR001270; Chaprnin_ClpA/B.
 IPR019489; Clp_ATPase_C.
 IPR004176; Clp_N.
 IPR023150; Dbl_Clp-N.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00004; AAA
 PF07724; AAA_2
 PF02861; Clp_N
 PF10431; ClpB_D2-small 
SMART
 SM00382; AAA
 SM01086; ClpB_D2-small 
PROSITE
 PS00870; CLPAB_1
 PS00871; CLPAB_2 
PRINTS
 PR00300; CLPPROTEASEA.