CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043282
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Differentially-expressed in FDCP 8 homolog 
Protein Synonyms/Alias
  
Gene Name
 DEF8 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
113RLIHLRLKLQELKDPubiquitination[1]
118RLKLQELKDPNEDEPubiquitination[1, 2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 177 AA 
Protein Sequence
MRGGGQAHLN PFNKQSGPRQ HEQGPGEEVP DVTPEEALPE LPPGEPEFRC PERVMDLGLS 60
EDHFSRPVGL FLASDVQQLR QAIEECKQVI LELPEQSEKQ KDAVVRLIHL RLKLQELKDP 120
NEDEPNIRVL LEHRFYKEKS KSVKQTCDKC NTIIWGLIQT WYTCTGCYYR CHSKCLN 177 
Gene Ontology
 GO:0035556; P:intracellular signal transduction; IEA:InterPro. 
Interpro
 IPR002219; Prot_Kinase_C-like_PE/DAG-bd. 
Pfam
  
SMART
  
PROSITE
 PS50081; ZF_DAG_PE_2 
PRINTS