CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017423
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Membrane magnesium transporter 1 
Protein Synonyms/Alias
 ER membrane protein complex subunit 5; Transmembrane protein 32 
Gene Name
 MMGT1 
Gene Synonyms/Alias
 EMC5; TMEM32 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
187LSSNTSLKLRKLESLubiquitination[1, 2, 3]
Reference
 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789
Functional Description
 Mediates Mg(2+) transport (By similarity). 
Sequence Annotation
  
Keyword
 Alternative splicing; Complete proteome; Endoplasmic reticulum; Endosome; Golgi apparatus; Magnesium; Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 131 AA 
Protein Sequence
MTPLGSGPPR EASIAQPSGF STTETLCAQD FSDVIFLRRA DTRRWKKKQL RRPSLLLLGC 60
CSFGIMAPSL WKGLVGIGLF ALAHAAFSAA QHRSYMRLTE KEDESLPIDI VLQTLLAFAV 120
TCYGIVHIAG EFKDMDATSE LKNKTFDTLR NHPSFYVFNH RGRVLFRPSD TANSSNQDAL 180
SSNTSLKLRK LESLRR 196 
Gene Ontology
 GO:0005769; C:early endosome; ISS:UniProtKB.
 GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
 GO:0072546; C:ER membrane protein complex; IDA:UniProtKB.
 GO:0005794; C:Golgi apparatus; ISS:UniProtKB.
 GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
 GO:0015095; F:magnesium ion transmembrane transporter activity; ISS:UniProtKB. 
Interpro
 IPR018937; Magnesium_transport. 
Pfam
 PF10270; MMgT 
SMART
  
PROSITE
  
PRINTS