CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-004805
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Choline transport protein 
Protein Synonyms/Alias
  
Gene Name
 HNM1 
Gene Synonyms/Alias
 CTR; CTR1; YGL077C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
25SSNASMHKRDLRVEEubiquitination[1]
35LRVEEEIKPLDDMDSubiquitination[1]
43PLDDMDSKGAVAADGubiquitination[1]
562NEHVPWGKK******ubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
 Sole choline transporter in yeast. 
Sequence Annotation
 MOD_RES 22 22 Phosphoserine.
 MOD_RES 42 42 Phosphoserine.
 CARBOHYD 7 7 N-linked (GlcNAc...) (Potential).
 CARBOHYD 20 20 N-linked (GlcNAc...) (Potential).
 CARBOHYD 248 248 N-linked (GlcNAc...) (Potential).
 CARBOHYD 341 341 N-linked (GlcNAc...) (Potential).  
Keyword
 Amino-acid transport; Complete proteome; Glycoprotein; Membrane; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 563 AA 
Protein Sequence
MSIRNDNASG GYMQPDQSSN ASMHKRDLRV EEEIKPLDDM DSKGAVAADG EVHLRKSFSL 60
WSILGVGFGL TNSWFGISTS MVAGISSGGP MMIVYGIIIV ALISICIGTS LGELSSAYPH 120
AGGQFWWSLK LAPPKYKRFA AYMCGSFAYA GSVFTSASTT LSVATEVVGM YALTHPEFIP 180
KRWHIFVCFE LLHLFLMFFN CYGKSLPIIS SSSLYISLLS FFTITITVLA CSHGKFNDAK 240
FVFATFNNET GWKNGGIAFI VGLINPAWSF SCLDCATHMA FEVEKPERVI PIAIMGTVAI 300
GFVTSFCYVI AMFFSIQDLD AVLSSTTGAP ILDIYNQALG NKSGAIFLGC LILFTSFGCV 360
IACHTWQARL CWSFARDNGL PLSRLWSQVN PHTGVPLNAH LMSCAWITLI GLLYLASSTA 420
FQSLITGCIA FLLLSYIIPV ICLLAKKRNI AHGPFWLGKF GFFSNIVLLG WTVFSVVFFS 480
FPPVLPVTKD NMNYVCVVIV GYTAYSILYW KYKGKKEFHA LEESENEQAE YSNNFDTIED 540
SREFSVAASD VELENEHVPW GKK 563 
Gene Ontology
 GO:0016021; C:integral to membrane; ISM:SGD.
 GO:0005886; C:plasma membrane; ISS:SGD.
 GO:0015171; F:amino acid transmembrane transporter activity; IEA:InterPro.
 GO:0015220; F:choline transmembrane transporter activity; IMP:SGD.
 GO:0034228; F:ethanolamine transmembrane transporter activity; IGI:SGD.
 GO:0031460; P:glycine betaine transport; IMP:SGD. 
Interpro
 IPR002293; AA/rel_permease1.
 IPR004756; AA_permease.
 IPR004840; Amoino_acid_permease_CS. 
Pfam
  
SMART
  
PROSITE
 PS00218; AMINO_ACID_PERMEASE_1 
PRINTS