UniProt Accession

 G3UZG8_MOUSE; G3UZG8 

Genbank Protein ID

 AC159324; CR974568 

Genbank Nucleotide ID

  

Protein Name

 DNA (cytosine-5)-methyltransferase 3A 

Protein Synonyms/Alias

  

Gene Name

 Dnmt3a 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
62	GMVRHQGKIMYVGDV	acetylation	[1]

Reference

 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 107 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:MGI.
 GO:0005720; C:nuclear heterochromatin; IDA:MGI.
 GO:0003682; F:chromatin binding; IDA:MGI.
 GO:0003886; F:DNA (cytosine-5-)-methyltransferase activity; IDA:MGI.
 GO:0003677; F:DNA binding; IDA:MGI.
 GO:0071230; P:cellular response to amino acid stimulus; IDA:MGI.
 GO:0043045; P:DNA methylation involved in embryo development; IMP:MGI.
 GO:0006346; P:methylation-dependent chromatin silencing; IDA:MGI.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.
 GO:0006349; P:regulation of gene expression by genetic imprinting; IMP:MGI.
 GO:0007283; P:spermatogenesis; IMP:MGI. 

Interpro

 IPR018117; C5_DNA_meth_AS.
 IPR001525; C5_MeTfrase. 

Pfam

 PF00145; DNA_methylase 

SMART

  

PROSITE

 PS00094; C5_MTASE_1 

PRINTS