CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013899
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Synaptosomal-associated protein 47 
Protein Synonyms/Alias
 SNAP-47; Epididymis luminal protein 170; Synaptosomal-associated 47 kDa protein 
Gene Name
 SNAP47 
Gene Synonyms/Alias
 C1orf142; HEL170; SVAP1 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
103SSIVEIKKEASHFIFubiquitination[1]
176GLMAGSQKRLEDTARubiquitination[1, 2]
201SVMRGLDKMESDLEVubiquitination[1, 2]
230PFSSKLWKTPPETKPubiquitination[2]
251TSCEPFGKEGILIKIubiquitination[2]
257GKEGILIKIPAVISHubiquitination[2]
271HRTESHVKPGRLTVLubiquitination[1]
304REDVDDIKVHSPYEIubiquitination[1, 2]
320IRQRFIGKPDMAYRLubiquitination[2]
331AYRLISAKMPEVIPIubiquitination[2]
345ILEVQFSKKMELLEDubiquitination[1]
346LEVQFSKKMELLEDAubiquitination[2]
367RTSSPAEKSCSVWHAubiquitination[2]
455RATLTIDKHNRRMKRubiquitination[2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
 Plays a role in intracellular membrane fusion (By similarity). 
Sequence Annotation
 DOMAIN 154 216 t-SNARE coiled-coil homology 1.
 DOMAIN 401 463 t-SNARE coiled-coil homology 2.  
Keyword
 Alternative splicing; Coiled coil; Complete proteome; Cytoplasm; Membrane; Polymorphism; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 464 AA 
Protein Sequence
MRAARRGLHC AGAERPRRRG RLWDSSGVPQ RQKRPGPWRT QTQEQMSRDV CIHTWPCTYY 60
LEPKRRWVTG QLSLTSLSLR FMTDSTGEIL VSFPLSSIVE IKKEASHFIF SSITILEKGH 120
AKHWFSSLRP SRNVVFSIIE HFWRELLLSQ PGAVADASVP RTRGEELTGL MAGSQKRLED 180
TARVLHHQGQ QLDSVMRGLD KMESDLEVAD RLLTELESPA WWPFSSKLWK TPPETKPRED 240
VSMTSCEPFG KEGILIKIPA VISHRTESHV KPGRLTVLVS GLEIHDSSSL LMHRFEREDV 300
DDIKVHSPYE ISIRQRFIGK PDMAYRLISA KMPEVIPILE VQFSKKMELL EDALVLRSAR 360
TSSPAEKSCS VWHAASGLMG RTLHREPPAG DQEGTALHLQ TSLPALSEAD TQELTQILRR 420
MKGLALEAES ELERQDEALD GVAAAVDRAT LTIDKHNRRM KRLT 464 
Gene Ontology
 GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.
 GO:0016020; C:membrane; IEA:UniProtKB-KW.
 GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. 
Interpro
 IPR000727; T_SNARE_dom. 
Pfam
  
SMART
  
PROSITE
 PS50192; T_SNARE 
PRINTS