UniProt Accession

 B0BN46_RAT; B0BN46; E9PSJ6 

Genbank Protein ID

 AABR06036819; BC158680; CH473962 

Genbank Nucleotide ID

 AAI58681.1; EDL98798.1 

Protein Name

 Grhpr protein 

Protein Synonyms/Alias

 Protein Grhpr; RCG54768, isoform CRA_a 

Gene Name

 Grhpr 

Gene Synonyms/Alias

 rCG_54768 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
72	RLSDRVDKKLLDAAG	acetylation	[1]
73	LSDRVDKKLLDAAGA	acetylation	[1]
101	HLALDEIKKRGIRVG	acetylation	[1]
180	QAIARRLKPFGVQRF	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 335 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; IDA:RGD.
 GO:0031406; F:carboxylic acid binding; IPI:RGD.
 GO:0008465; F:glycerate dehydrogenase activity; IDA:RGD.
 GO:0030267; F:glyoxylate reductase (NADP) activity; IDA:RGD.
 GO:0016618; F:hydroxypyruvate reductase activity; IDA:RGD.
 GO:0051287; F:NAD binding; IDA:RGD.
 GO:0050661; F:NADP binding; IDA:RGD.
 GO:0070402; F:NADPH binding; IEA:Compara.
 GO:0043648; P:dicarboxylic acid metabolic process; IDA:RGD.
 GO:0007588; P:excretion; IEA:Compara.
 GO:0051259; P:protein oligomerization; IEA:Compara. 

Interpro

 IPR006139; D-isomer_2_OHA_DH_cat_dom.
 IPR006140; D-isomer_2_OHA_DH_NAD-bd.
 IPR016040; NAD(P)-bd_dom. 

Pfam

 PF00389; 2-Hacid_dh
 PF02826; 2-Hacid_dh_C 

SMART

  

PROSITE

 PS00671; D_2_HYDROXYACID_DH_3 

PRINTS